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In this paper, an aggregate system level modeling and analysis framework is proposed to facilitate the integration and design of advanced life support systems (ALSS). As in process design, the goal is to choose values for the degrees of freedom that achieve the best overall ALSS behavior without violating any system constraints. At the most fundamental level, this effort will identify the constraints and degrees of freedom associated with each subsystem and provide estimates of the system behavior and interactions involved in ALSS. This work is intended to be a starting point for developing insights into ALSS from a systems engineering point of view. At this level, simple aggregate static input/output mapping subsystem models from existing data and the NASA ALS BVAD document are used to debug the model and demonstrate feasibility.