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The effectiveness of ultraviolet (UV) disinfection is governed by the UV dose to which microorganisms are exposed. In treatment operations, all UV disinfection systems deliver a distribution of UV doses. The ability to accurately estimate the dose distribution delivered by an operating UV system is a critical aspect of its design. Moreover, the availability of tools to accurately predict the dose distribution for an existing UV system makes it possible to develop reliable, quantitative predictions of process performance in these systems. The dose distribution can be estimated by employing computational fluid dynamics (CFD) and UV radiation intensity field modeling. UV dose-distribution data is then coupled with UV dose-response behavior for target microorganisms to yield an estimate of process performance.

As part of the NASA Specialized Center of Research and Training for Advanced Life Support (NSCORT-ALS) at Purdue University, a complementary disinfection process, which uses ultraviolet (UV) radiation as the primary disinfectant and iodine as the secondary, residual disinfectant, is being developed. UV radiation was selected as the primary disinfectant because it is effective at inactivating a broad spectrum of microorganisms and has minimal potential for the formation of disinfection byproducts. Iodine, which is effective at inactivating many microorganisms and is less likely to react and form disinfection byproducts than other halogens, was selected as the residual disinfectant because it has the potential for dual use as an on-line UV monitor, as well as a disinfectant.