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Flouroelastomers and silicone rubbers are commonly employed in static and dynamic seals for automotive applications. In order to prevent premature failures and leakages caused by swelling and/or changes in their mechanical properties, materials for seals are selected according to their compatibility with the environment and fluids involved in the engine operation. Thus, in particular, the use of new fuels and additives in automotive engines requires the assessment of compatibility with common sealing elastomers to prevent failures. Currently, Jatropha oil is being used as a renewable source of fuel in diesel engines for electricity production, transport or agricultural mechanization in various countries. It is used either as biodiesel or as straight vegetable oil (SVO) since it has good heating power and provide exhaust gas with almost no sulfur or aromatic polycyclic compounds. However, the compatibility of elastomers with this SVO has not been investigated yet.