This paper documents the current realities of in-vehicle navigation systems in terms of their functionality, scope and responsiveness. It discusses the evolution of these systems with the advent of wireless communications. Addressed are the issues associated with delivery and utilization of real-time traffic, incident, and weather information to and by in-vehicle navigation systems. Also discussed are other High-level in-vehicle decisions that can be supported by the marriage of wireless communications with in-vehicle navigation. Applications considered range from the choosing of alternate waypoints and destinations (where to get gas, where to park), to the host of nRouteCommerce transactions that can be more efficiently achieved with the support of in-vehicle navigation (reserving a parking space, resetting household thermostats as you approach home). Implications on driver workload, in-vehicle processing, wireless bandwidth and Internet traffic are discussed.