Spray-guided gasoline direct injection demonstrates great potential to reduce both fuel consumption and pollutant emissions. However, conventional materials used in high-pressure pumps wear severely under fuel injection pressures above 20 MPa as the lubricity and viscosity of gasoline are very low. The use of ceramic components promises to overcome these difficulties and to exploit the full benefits of spray-guided GDI-engines. As part of the Collaborative Research Centre “High performance sliding and friction systems based on advanced ceramics” at Karlsruhe Institute of Technology, a single-piston high-pressure gasoline pump operating at up to 50 MPa has been designed. It consists of 2 fuel-lubricated sliding systems (piston/cylinder and cam/sliding shoe) that are built with ceramic parts. The pump is equipped with force, pressure and temperature sensors in order to assess the behaviour of several material pairs. The results presented in this paper show great potential for using either silicon carbide or SiAlON in high-pressure injection pumps for gasoline with operating pressures of up to 50 MPa.