This paper presents ‘Virtual Shaker Table’: a CAE method that enables random frequency structural response and random vibration fatigue analyses of a battery system. The Virtual Shaker Table method is a practical and systematic procedure that effectively assesses battery system vibration performance prior to final design, build and testing. A random structural frequency response analysis identifies the critical frequencies and modes at which the battery system is excited by random inputs. Fatigue life may be predicted after PSD stresses have been ascertained. This method enables frequency response analysis techniques to be applied quickly and accurately, thereby allowing assessment of multiple design alternatives. Virtual Shaker Table facilitates an elegant solution to some of the significant challenges inherent to complex battery system design and integration. Virtual Shaker Table has been used successfully to simulate vibration testing of the GM Volt battery system in the lab environment.