Partially Premixed Combustion is a concept able to combine low smoke and NOx emissions with high combustion controllability and efficiency. It is of interest to be able to utilize PPC in a large operating region in order to meet the Euro VI emission legislation without relying on NOx aftertreatment.This paper investigates the differences in PPC characteristics for three fuels; Diesel Swedish Mk 1, Low Octane Gasoline (70 Octane) and US Standard Gasoline (87 Octane). Engine operating conditions, combustion characteristics, emissions and efficiency are in focus.The experiments were carried out at a range of operating points on a Volvo MD13 which is a six-cylinder heavy-duty engine. At each operating point three combinations of EGR level and λ-value were evaluated. 1. High EGR/High λ, 2. High EGR/Reduced λ, and 3. Reduced EGR/High λ.Further, for all these three conditions, four combustion timings were tested reaching from advanced combustion timing at 3 CAD ATDC to retarded combustion timing at 9 CAD ATDC. The indicated load and the combustion timing were controlled cylinder individually by a feedback controller.