Good performance of fuel system is critical for fuel efficiency, combustion process, emissions, start ability, acceleration and combustion noise. The fuel system design is a complicated process. Simulation tools are playing an important role in virtual design. They are used to evaluate performance, optimize the design, and provide understanding for performance or durability related problem. This paper illustrates how a 1D system simulation tool is utilized to investigate an observed failure of a high pressure hose. The simulation identifies the dominant modes in the fuel system and determines the engine speed at which the fuel system mode is excited. At various engine speeds, the simulation investigates the magnitude of pressure pulsation in the high pressure hose of the fuel system. Finally, the 1D simulation provides the design optimization approach to suppress the oil pressure pulsation and reduce the structure vibration. The test shows that 1D simulation result correlates well with the test data. The vibration reduction approach provided by 1D simulation effectively reduces the oil pressure pulsation and structure vibration in the fuel system. The paper presents the integrated analysis procedure and methods of modal analysis and vibration reduction in fuel system.