This paper presents the way to optimize vehicle AC system TXV to meet the various AC system requirements. It discusses vehicle AC system TXV sizing and selection process. In today's automotive industry, sizing and selecting the TXV is more complicated than before as various new components are introduced such as external control compressor, internal control compressors and internal heat exchanger etc. These components complicated the system interaction among the components. Thus it requires mapping TXV characteristic to meet the system demand. Sizing TXV capacity, it must start with the vehicle heat load requirement. The type of TXV (i.e. cross charge or parallel charge head) is determined by the system configuration such as compressor, evaporator, and condenser type and with or without internal heat exchanger, etc. To optimize TXV in the system involves in evaluating TXV characteristic and cooling capacity in the various AC operating conditions. The criteria for the evaluation can determine how the selected TXV behaviors in the real world.The paper also discusses how the TXV manufacture 4-Q diagram can be utilized in optimizing TXV in the system. The case study shows how the presented TXV sizing and selection process works. The recommended TXV evaluation criteria are also discussed in the paper.