The National Highway Traffic Safety Administration has performed research investigating the Test Device for Human Occupant Restraint 50th male (THOR-50M) response in Oblique crash tests. This research is being expanded to investigate THOR-50M in the driver position in a 56 km/h frontal impact crash. Hybrid III 5th percentile adult female (AF05) anthropomorphic test devices (ATDs) were used in this testing to evaluate the RibEye Deflection Measurement System. The AF05 ATDs were positioned in the right front passenger and right rear passenger seating positions. For the right front passenger, the New Car Assessment Procedure (NCAP) seating procedure was used, except the seat fore-aft position was set to mid-track. For the right rear passenger, the seating followed the FMVSS No. 214 Side Impact Compliance Test Procedure. The NCAP frontal impact test procedure was followed with additional vehicle instrumentation and pre/post-test measurements. Results from this test series were compared with previous NCAP crash tests. The THOR-50M showed similar kinematics to the Hybrid III 50th but predicted a higher risk of chest and femur injury. The mid-track seat position of the right front passenger AF05 led to lower levels of femur compression loading due to additional distance to the dash. BrIC for the driver and front passenger showed higher injury risk than HIC15. In all vehicles, the rear seat AF05 predicted a substantially higher risk of head, neck and chest injury than the right front passenger. The AF05 RibEye output showed a higher peak deflection (x-axis) than the chest potentiometer.