This article delineates the importance of infrastructure and its related aspects on sustainability of transportation on global and local context. Almost 7% of the GDP in India is spent on transportation and 6% of the CO2 emissions in the world is due to transportation. In countries like India, the road transport has significantly grown over other forms of mobility. This articles introduces different forms of transportations that exists today and the importance of sustainability in transportation sector. Sustainable transportation depends on development of infrastructure to enable smart transport solutions involving intelligent transport system, electric mobility, information management, vehicle health monitoring, advanced traffic management system and driver assistance system in a vehicle. The challenges includes existing transport operations, environmental impact and complexity of existing transport network. Future sustained mobility should gradually move towards alternate energy source preferably hydrogen and fuel cell based systems. Several demonstrations has been observed around the world in transport sector with non-carbon based energy source for mass mobility. This articles gives several such interesting examples. Future recommendations in this article promotes powered bicycles, cable cars and dual mode vehicles as a means of sustained mobility. Other recommendations includes economy mode in vehicles to save fuel, double decker coaches for suburban railways to reduce road commuters, work clusters for service sectors as an alternate means for reducing road traffic and pollution.