Homogeneous Charge Compression Ignition (HCCI) combustion has attracted widespread interest in recent years as a clean, high-efficiency combustion system. However, it is difficult to control the ignition timing in HCCI engines because they lack a physical means of inducing ignition. Another issue of HCCI engines is their narrow operating range because of misfiring that occurs at low loads and abnormal combustion at high loads. As a possible solution to these issues, this study focused on the application of a streamer discharge in the form of non-equilibrium plasma as a technique for assisting HCCI combustion. Experiments were conducted with a four-stroke single-cylinder engine fitted with an ignition electrode in the combustion chamber. A streamer discharge was continuously generated in the cylinder during a 720-degree interval from the intake stroke to the exhaust stroke. The results confirmed that the application of a streamer discharge to an HCCI engine enabled ignition under conditions where it would not ordinarily be possible. The effect on promoting combustion was obtained even for lean combustion and under the application of exhaust gas recirculation. However, that effect was diminished under a condition of a high boost pressure.