Vehicles are required durability in various environments all over the world. Especially water resistance on flooded roads is one of the important issues. To solve this kind of problem, a CFD technology was established in order to predict the water resistance performance of the vehicle at the early development stage. By comparison with vehicle tests on flooded roads, it is clarified the following key factors are required for accurate prediction; the vehicle velocity change, the vehicle height change and the air intake flow rate. Moreover, these three key factors should be appropriately determined from vehicle and engine specification to predict water intrusion for flooded roads at the early stage of development. In this paper, a methodology which determines appropriate analysis conditions mentioned above for flooding simulation from vehicle and engine specification is described. The methodology enables us to determine whether the vehicle provides sufficient waterproofness. Further, it is confirmed that the CFD with the methodology can successfully reproduce critical phenomena for water intrusion into the air intake duct.