Due to the increase of mining production and rising labor costs, manufacturers of construction and mining equipment are engaged in developing large tonnage mining truck with good dynamic performance and high transport efficiency. This paper focuses on the improvement of the dynamic performance of a 52t off-highway dump truck. According to the characteristics of its operating cycle, electric auxiliary drive system is installed in the front axle aiming at improving the utilization rate of ground adhesion. The new all-wheel drive hybrid electric system makes it possible for dump truck transports at a higher velocity. Both the conventional dump truck model and the new all-wheel drive hybrid truck model are built based on the AVL-Cruise platform. Meanwhile, under the premise of enough dynamic performance, fuel consumption can be minimized by collaborative optimization in Isight. Multi-island genetic algorithm is adopted to get proper powertrain parameters for its wide use in finding a global optimal solution. The collaborative optimization results show that the new hybrid dump truck obtains high dynamic performance without sacrificing the fuel economy. By comparing the simulation results we find that the maximum velocity of full load all-wheel drive hybrid electric dump truck increases by 19% at 8% slope, by 21.4% at 12% slope. All these improvements are of great significance to the transport efficiency and fuel economy of the dump truck.