Battery State of Charge (SOC) constraints are used to prevent the battery in Hybrid Electric Vehicles (HEVs) from over-charging or over-discharging. These constraints strongly influence the power-split of the HEV. This paper presents results on how Battery State of Charge (SOC) constraints effects Lithium ion battery aging and fuel economy when using the Equivalent Consumption Minimization Strategy (ECMS). The vehicle studied is the Honda Civic Hybrid. The battery used is A123 Systems’ ANR26650 battery cell. Vehicle simulation uses multiple combinations of highway and city drive cycles. For each combination of drive cycles, nine SOC constraints ranges are used. Battery aging is evaluated using a semi-empirical model combined with the accumulated Ah-throughput method which uses, as an input, the battery SOC trajectory from the vehicle simulations. The simulation results provide insight into how SOC constraints effect fuel economy as well as battery aging. The paper concludes with a discussion of the balance between fuel economy and battery aging by examining performance results with various SOC constraints.