This paper present the machinability investigation of X-750 Inconel alloy using two coated carbide inserts. This alloy is one of the most demanding advanced engineering materials due to its superior quality. Moreover, the comparative process benefit analysis of machinability aspect using coated carbide inserts are reported few. To collect the experimental data, the L16 experimental design plan is used to perform the experiment for a machining length of 40 mm. Four level of cutting speed (70,120,170,220 m/min), feed rate (0.1, 0.15, 0.2, 0.25 mm/rev) and cutting depth (0.3, 0.4, 0.5, 0.6 mm) were the cutting/machining parameters used. Cutting forces, surface roughness, flank and crater wear are considered as target functions. With application of response surface, coupled with desirability analysis, the optimal levels of combination are determined. With determined optimal levels, tool life study has been carried out to compare the effectiveness of cutting inserts.