The reasons for conducting research in a university are presented and discussed. It is concluded that fuel-engine studies are compatible with these reasons and therefore are well suited for university research. Past studies in this field are summarized and unanswered questions and future topics suitable for university investigation are suggested. Included in the topics discussed are: instrumentation, thermodynamic description of working fluids, fuel vaporization and atomization, combustion, and instantaneous heat transfer and mass flow rates. The steps that need to be taken to ensure continuing university interest in fuel-engine studies are presented.