This paper presents predictions of fatigue crack initiation life for three distinctly different, irregular load histories, each applied to keyhole-notched compact tension specimens at several maximum load levels and using two different structural steels. Work leading to this paper was done in conjunction with the cooperative research program of the SAE Fatigue Design and Evaluation Committee. Three computerized prediction methods (Landgraf, Wetzel, and a Nominal Stress Range approach) are used. All predictions are based on load histories condensed to 10% of their original number of reversals by the “Racetrack Method.” This method, which is described in detail, selects the most damaging overall ranges in an irregular load history while preserving the sequence of the original loading. Predictions are compared with test data for the two dozen combinations of loading type and level and steel used. Comments are made on the relative merits of the different prediction methods.