In-plant trailers constitute a large portion of material handling system in manufacturing plants of the automotive industry. The trailers are among the most intensive noise sources, with radiated noise reaching 110 dBA (Leq). High dynamic loads are also generated on the floor and in the trailer structure. These dynamic loads lead to maintenance problems and inflated inventory of the trailers. Principal mechanisms responsible for generating noise and dynamic loads are identified and treatments to reduce noise and dynamic loads have been developed and investigated on standard trailers. Test results show: for an empty trailer, application of the proposed nonlinear suspension reduces noise 16–18 dBA (Leq) and dynamic load 10 times; for a trailer with an empty rack, application of the proposed nonlinear rack cushion leads to 3–5 dBA (Leq) noise reduction in addition to 8–10 dBA (Leq) reduction due to the suspension. The suspension allows the use of plain steel wheels instead of expensive and nondurable polyurethane treaded wheels, and results in large projected savings in maintenance and reduced inventory of the trailers.