A Vehicle-Engine-Cooling (VEC) system computer simulation model was used to study the transient performance of control devices and their temperature settings on oil, coolant and cab temperatures. The truck used in the study was an International Harvester COF-9670 cab over chassis heavy-duty vehicle equipped with a standard cab heater, a Cummins NTC-350 diesel engine with a McCord radiator and standard cooling system components and aftercooler. Input data from several portions of a Columbus to Bloomington, Indiana route were used from the Vehicle Mission Simulation (VMS) program to determine engine and vehicle operating conditions for the VEC system computer simulation model. The control devices investigated were the standard thermostat, the Kysor fan-clutch and shutter system. The effect of shutterstat location on shutter performance along with thermostat, shutter and fan activation temperature settings were investigated for ambient temperatures of 32, 85 and 100°F. The results show that the thermostat-shutter-fan coolant temperature control combination set at 180, 195 and 200°F respectively, resulted in the best coolant temperature control and cab comfort levels over the range of ambient temperatures.