A three dimensional computational fluid dynamics program is used to simulate theoretically the scavenging process in the loop-scavenged two-stroke cycle engine. The theoretical calculation uses the k - ε turbulence model and all calculations are confined to the in-cylinder region. The calculation geometry is oriented towards five actual engine cylinders which have been tested under firing conditions for the normal performance characteristics of power, torque, and specific fuel consumption. The same five engine cylinders have also been experimentally tested on a single-cycle gas testing rig for their scavenging efficiency - scavenge ratio characteristics. The ranking of the cylinders in order of merit in terms of scavenging efficiency by both the rig and the theoretical calculations is shown to be in good agreement with the evidence provided by the actual firing engine test results. More interestingly, the theoretical CFD approach provides real insight into the in-cylinder flow behaviour and the loop-scavenging process at both the crank-angle by crank-angle level and its resulting overall effects.