The preliminary design of the nation’s Space Station is presently being developed. The Environmental Control and Life Support System (ECLSS), consisting of regenerative and nonregenerative technologies, has progressed through a series of trade studies including evaluation of the closure and distribution within the evolutionary Space Station configuration. The analysis has included the identification of the time-critical functions, redundancy (backup) management, definition of common subsystem interfaces and quantification of technology options for the process equipment. Each technology has been characterized by its physical characteristics of weight, power, volume, heat rejection, etc. Summaries of the trade study findings for the overall ECLSS in terms of physical characteristics and the impact of selected technologies is presented.