Valve wear has been identified as a major durability problem in natural gas fueled reciprocating engines. Over the years, progress has been made to alleviate this problem through improved valve design and materials development. Recently high performance ceramics have shown promise for wear component applications. This paper presents the results of a valve train component materials investigation supported by the Gas Research institute. Testing tools and methods are described. The testing program culminated in a 300 hour component test in a full size turbocharged natural gas engine. Results of the engine test appeared to confirm preceding laboratory tests. Sintered silicon nitride valve seat inserts and Stellite 6 coated 21-12 stainless steel valves appeared to be the most promising material combination evaluated.