The needs for life sciences research and facilities on Space Station in Phase 2, based on future space exploration and utilization plans, are discussed. The assumed scenario involves a Lunar Base, manned missions to Mars, and an orbiting Space Colony for the production of Solar Power Satellites permitting replacement of fossil fuels by the middle of the next century. From this scenario, the contours of a life sciences program for the period after 1998 are derived. Based on the main elements of such a program, the major new life sciences facilities needed in Phase 2 are identified. It is concluded that a full-length dedicated life sciences module and an attached short module with large centrifuge and animal research facilities, as well as a man-rated variable research facility and other attached facilities are needed. A proposed deployment schedule for these facilities is presented. Should replacement of fossil fuels by space-derived solar power not be necessary, then the same elements and facilities will be needed, but the schedule can be relaxed.