General purpose tank vehicles often carry partial loads in view of variations in the weight density of the liquid cargo and are thus subject to slosh loads during highway manoeuvres. The magnitude of destabilizing forces and moments due to liquid slosh is strongly related to a number of vehicle and tank design factors, such as tires, suspension, articulation mechanism, weights and dimensions, tank geometry and fill level. The rollover threshold of the tank vehicle is compared to that of an equivalent rigid cargo vehicle to demonstrate the destabilizing effects of liquid slosh. The rollover threshold of the tank vehicle is evaluated for a number of tank design factors. Influence of tank size and cross-section on the rollover threshold of the tank vehicles is investigated. The study concludes that the lateral load shift and thus the rollover threshold is strongly related to the tank cross-section geometry. The rollover threshold of the articulated vehicle carrying a compartmented tank is investigated and an optimal order of unloading various compartments is presented.