The replacement with plastic of an important component, formerly in steel, in the timing drive of a heavily duty diesel engine has been studied and realized. The substituted part is the toothed coupling connecting the injection pump to the timing drive. Torque that stresses the coupling has been measured with laboratory tests. The tooth stresses have been calculated with FEM analysis. Finally, fatigue tests have been carried out directly on the engine at different loadings. The test results are consistent with the predicted behavior of this component.