Successful operation of life support systems for space exploration missions of the future will require unique sophisticated sensor systems for highly dependable operation, i.e., autonomous and fault tolerant. These sensor systems will require the use of multifunctional in situ sensors that are strategically located throughout the life support systems. These sensors will communicate through control loops that are hierarchically interconnected at several levels of the life support system. Development of the sensor system must be done synergistically with the integration and testing of the subsystems, and their process units, as they are assembled and tested. The plan for proceeding with the sensor systems development and the integration with the test bed assembly and operation is described in this paper.