This paper describes how the SP-100 Space Reactor Power System (SRPS) can be tailored to meet the specific requirements for a lunar surface power system to meet the needs of the consolidation and utilization phases outlined in the 90-day NASA SEI study report. This same basic power system can also be configured to obtain the low specific masses needed to enable robotic interplanetary science missions employing Nuclear Electric Propulsion (NEP). In both cases it is shown that the SP-100 SRPS can meet the specific requirements. For interplanetary NEP missions, performance upgrades currently being developed in the area of light weight radiators and improved thermoelectric material are assumed to be technology ready in the year 2000 time frame. For lunar applications, some system rearrangement and enclosure of critical components are necessary modifications to the present baseline design.