This paper discusses the techniques and technologies Human Factors uses to incorporate safety, comfort, and advancing technologies in the aircraft cabin. Specific topics addressed include accommodation for various user populations (e.g., reach, clearances, lifting), operation of required equipment, information transfer, passenger comfort and convenience, as well as passenger and flight attendant behavioral issues. The content includes a review of typical human-cabin interface case studies. These design projects include a description of the multiple-design requirements that cabin enhancements must meet. Finally, the paper includes a description of on-going efforts to increase the extent and quality of the human-aircraft cabin interface.