The purpose of this paper is to describe results of work performed to develop engine stand equipment and procedures suitable for the study of octane related phenomenon in engines currently provided in vehicles. Realistic engine operation under well controlled conditions is provided by novel vehicle simulation stands. Electronic knock detection provides precise information regardless of engine materials that can affect knock signal frequency or amplitude. Knock rating procedures test the engine through a speed range that duplicates the most severe accelerating conditions of a vehicle. Test protocols provide the tools to study the effect of potential gasoline additives designed to alter the octane requirement appetite of a cross section of modern engines.