A generalized computer model for prediction of transient exhaust soot and response of turbocharged diesel engines is developed. It includes detailed thermodynamic and dynamic processes. This model utilizes a multi-zone combustion submodel that emphasizes simple and economical calculations for combustion behavior and zonal soot, so overall transient exhaust soot can be predicted.This model is applied to a turbocharged diesel engine. The steady state exhaust soot and performance are calculated and validated, and on the basis, the exhaust soot and response under three classes of transient operating conditions are predicted.The parametric study is carried out by using this model. The effects of valve overlap period, exhaust manifold volume, turbocharger inertia and ambient pressure are predicted.Applications of this model have proved that it is a convenient analytical tool in the study for turbocharged diesel engines.