The effects of strain path on formability and microstructural evolution with strain in two low-carbon steels were examined. The steels include a 0.008 wt. pct. C batch annealed 0.81 mm thick sheet and a 0.031 wt. pct. C continuously annealed0.74 mm sheet with essentially equivalent mechanical properties (YS: 230 MPa; UTS: 350 MPa; n: 0.18). The steels were subjected to various increments of prestrain in either uniaxial or biaxial tension, and forming limits were assessed in the samples after a strain path change to biaxial or uniaxial tension, respectively. Biaxial stretching prestrain lowers the uniaxial tension forming limit, while uniaxial tensile prestrain raises the biaxial stretching forming limit. The differences in forming response were also correlated with distinct dislocation cell structures. The effects of strain path on formability were shown to correlate with predictions based on a redundant strain model and a critical thickness strain model.