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The paper covers the NOx performance evaluation of an LNT + SCR system designed to meet the 2010 on-highway heavy-duty (HD) US EPA emission standards. The system combines a fuel reformer catalyst (REF), lean NOx trap (LNT), diesel particulate filter (DPF), and selective catalytic reduction (SCR) in series, to reduce engine-out NOx and PM. System NOx reduction performance was verified in an engine dynamometer test cell, using a 2007 7.6L medium-duty engine. System NOx performance was characterized using fresh LNT and SCR along with hydrothermal aged LNT and fresh SCR. Test results show levels consistent with EPA 2010 limits under various test conditions. Catalysts performance was characterized at eight steady engine-operating conditions (A100, B50, B75, A75, B100, C100, C75, C50, across a 13-mode Supplemental Emission Test (SET), and an on-highway Heavy Duty Federal Test Procedure (HD-FTP).