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After several decades of human spaceflight, the community of space-faring nations has accumulated a diverse and sometimes harrowing history of toxicological events that have plagued human space endeavors almost from the very beginning. Some lessons have been learned in ground-based test beds and others were discovered the hard way - when human lives were at stake in space. From such lessons one can build a risk-management framework for toxicological events to minimize the probability of a harmful exposure, while recognizing that we cannot predict all possible events. Space toxicologists have learned that relatively harmless compounds can be converted by air revitalization systems into compounds that cause serious harm to the crew.

NASA's Constellation Program includes the Orion, Altair, and Lunar Surface Systems (LSS) project offices. The first two elements, Orion and Altair, are manned space vehicles while the third element is broader and includes several subelements including Rovers and a Lunar Habitat. The upcoming planned missions involving these systems and vehicles include several risks and design challenges. Due to the unique thermal environment, many of these risks and challenges are associated with the vehicles' thermal control system. NASA's Exploration Systems Mission Directorate (ESMD) includes the Exploration Technology Development Program (ETDP). ETDP consists of several technology development projects. The project chartered with mitigating the aforementioned risks and design challenges is the Thermal Control System Development for Exploration Project.

The International Space Station (ISS) program is nearing an assembly complete configuration with the addition of the final resource node module in early 2010. The Node 3 module will provide critical functionality in support of permanent long duration crews aboard ISS. The new module will permanently house the regenerative Environment Control and Life Support Systems (ECLSS) and will also provide important habitability functions such as waste management and exercise facilities. The ISS program has selected the Port side of the Node 1 “Unity” module as the permanent location for Node 3 which will necessitate architecture changes to provide the required interfaces. The USOS ECLSS fluid and ventilation systems, Internal Thermal Control Systems, and Avionics Systems require significant modifications in order to support Node 3 interfaces at the Node 1 Port location since it was not initially designed for that configuration.

The Sublimator Driven Coldplate (SDC) is a unique piece of thermal control hardware that has several advantages over a more traditional thermal control system. The principal advantage is the possible elimination of a pumped fluid loop, potentially saving mass, power, and complexity. Because this concept relies on evaporative heat rejection techniques, it is primarily useful for short mission durations. Additionally, the concept requires a conductive path between the heat-generating component and the heat rejection device. Therefore, it is mostly a relevant solution for a vehicle with a relatively low heat rejection requirement and/or short transport distances. Tests were performed on coupons and an Engineering Development Unit (EDU) at NASA's Johnson Space Center to better understand the basic operational principles and to validate the analytical methods being used for the SDC development.

Lunar dust exposures occurred during the Apollo missions while the crew was in the lunar module on the moon's surface and especially when micro-gravity conditions were attained during rendezvous in lunar orbit. Crews reported that the dust was irritating to the eyes, and in some cases, respiratory symptoms were elicited. NASA's current vision for lunar exploration includes stays of 6 months on the lunar surface hence the health effects of periodic exposure to lunar dust in the habitat need to be assessed. NASA is performing this assessment with a series of in vitro and in vivo tests with authentic lunar dust. Our approach is to “calibrate” the intrinsic toxicity of lunar dust by comparison to a relatively low toxicity dust (TiO2) and a highly toxic dust (quartz) using intrapharyngeal instillation of the dusts to mice. A battery of indices of toxicity is assessed at various time points after the instillations.

A reconfigurable control system is an intelligent control system that detects faults within the system and adjusts its performance automatically to avoid mission failure, save lives, and reduce system maintenance costs. The concept was first successfully demonstrated by NASA between December 1989 and March 1990 on the F-15 flight control system (SRFCS), where software was integrated into the aircraft's digital flight control system to compensate for component loss by reconfiguring the remaining control loop. This was later adopted in the Boeing X-33. Other applications include modular robotics, reconfigurable computing structure, and reconfigurable helicopters. The motivation of this work is to test such control system designs for future long term space missions, more explicitly, the automation of life support systems.

We have completed preliminary tests that show the feasibility of an innovative concept for a spacesuit thermal control system using a lightweight, flexible heat pump/radiator. The heat pump/radiator is part of a regenerable LiCI/water absorption cooling device that absorbs an astronaut's metabolic heat and rejects it to the environment via thermal radiation at a relatively high temperature. We identified key design specifications for the system, demonstrated that it is feasible to fabricate the flexible radiator, measured the heat rejection capability of the radiator, and assessed the effects on overall mass of the PLSS. We specified system design features that will enable the flexible absorber/radiator to operate in a wide range of space exploration environments. The materials used to fabricate the flexible absorber/radiator samples were all found to be low off-gassing and many have already been qualified for use in space.

The Spacesuit Water Membrane Evaporator (SWME) is the baseline heat rejection technology selected for development for the Constellation lunar suit. The first SWME prototype, designed, built, and tested at Johnson Space Center in 1999 used a Teflon hydrophobic porous membrane sheet shaped into an annulus to provide cooling to the coolant loop through water evaporation to the vacuum of space. This present study describes the test methodology and planning to compare the test performance of three commercially available hollow fiber materials as alternatives to the sheet membrane prototype for SWME, in particular, a porous hydrophobic polypropylene, and two variants that employ ion exchange through non-porous hydrophilic modified Nafion. Contamination tests will be performed to probe for sensitivities of the candidate SWME elements to ordinary constituents that are expected to be found in the potable water provided by the vehicle, the target feedwater source.

As next generation space suit concepts enable extravehicular activity (EVA) mission capability to extend beyond anything currently available today, revolutionary advances in life support technologies are required to achieve anticipated NASA mission profiles than may measure years in duration and require hundreds of sorties. Since most life support systems require power, increased mass and volume efficiency of the energy storage materials can have a dramatic impact on reducing the overall weight of next generation space suits. ITN Energy Systems, in collaboration with Hamilton Sundstrand and the NASA Johnson Space Center's EVA System's Team, is developing multifunctional fiber batteries to address these challenges. By depositing the battery on existing space suit materials, e.g. scrim fibers in the thermal micrometeoroid garment (TMG) layers, parasitic mass (inactive materials) is eliminated leading to effective energy densities ∼400 Wh/kg.

Hamilton Sundstrand has developed a scalable evaporative heat rejection system called the Multi-Fluid Evaporator (MFE). It was designed to support the Orion Crew Module and to support future Constellation missions. The MFE would be used from Earth sea level conditions to the vacuum of space. This system combines the functions of the Space Shuttle flash evaporator and ammonia boiler into a single compact package with improved freeze-up protection. The heat exchanger core is designed so that radial flow of the evaporant provides increasing surface area to keep the back pressure low. The multiple layer construction of the core allows for efficient scale up to the desired heat rejection rate. A full-scale unit uses multiple core sections that, combined with a novel control scheme, manage the risk of freezing the heat exchanger cores. A four-core MFE prototype was built in 2007.

An EVA simulation with a medical contingency scenario was conducted in 2006 with the NASA Haughton-Mars and EVA Physiology System and Performance Projects, to develop medical contingency management and evacuation techniques for planetary surface exploration. A rescue/evacuation system to allow two rescuer astronauts to evacuate one incapacitated astronaut was evaluated. The rescue system was utilized effectively to extract an injured astronaut up a slope of15-25° and into a surface mobility rover for transport to a simulated habitat for advanced medical care. Further research is recommended to evaluate the effects of reduced gravity and to develop synergies with other surface systems for carrying out the contingency procedures.

Spacecraft radiators reject heat to their surroundings. Radiators can be deployable or mounted on the body of the spacecraft. NASA's Crew Exploration Vehicle is to use body mounted radiators. Coatings play an important role in heat rejection. The coatings provide the radiator surface with the desired optical properties of low solar absorptance and high infrared emittance. These specialized surfaces are applied to the radiator panel in a number of ways, including conventional spraying, plasma spraying, or as an appliqué. Not specifically designed for a weathering environment, little is known about the durability of conventional paints, coatings, and appliqués upon exposure to weathering and subsequent exposure to solar wind and ultraviolet radiation exposure. In addition to maintaining their desired optical properties, the coatings must also continue to adhere to the underlying radiator panel.

For NASA's Constellation Program, an Intravehicular Activity (IVA) and Extravehicular Activity (EVA) Life Support Umbilical System (LSUS) will be required to provide environmental protection to the suited crew during Crew Exploration Vehicle (CEV) cabin contamination or depressurization and contingency EVAs. The LSUS will provide the crewmember with ventilation, cooling, power, communication, and data, and will also serve as a crew safety restraint during contingency EVAs. The LSUS will interface with the Vehicle Interface Assembly (VIA) in the CEV and the Suit Connector on the suit. This paper describes the effort performed to develop concept designs for IVA and EVA umbilicals, universal multiple connectors, handling aids and stowage systems, and VIAs that meet NASA's mission needs while adhering to the important guiding principles of simplicity, reliability, and operability.

As part of preparing for the Crew Exploration Vehicle (CEV), the National Aeronautics and Space Administration (NASA) worked on developing the requirements to manage the fire risk. The new CEV poses unique challenges to current fire protection systems. The size and configuration of the vehicle resembles the Apollo capsule instead of the current Space Shuttle or the International Space Station. The smaller free air volume and fully cold plated avionic bays of the CEV requires a different approach in fire protection than the ones currently utilized. The fire protection approach discussed in this paper incorporates historical lessons learned and fire detection and suppression system design philosophy spanning from Apollo to the International Space Station.

Development of new air revitalization system (ARS) technology can initially be performed in a subscale laboratory environment, but in order to advance the maturity level, the technology must be tested in an end-to-end integrated environment. The Air Revitalization Technology Evaluation Facility (ARTEF) at the NASA Johnson Space Center (JSC) serves as a ground test bed for evaluating emerging ARS technologies in an environment representative of spacecraft atmospheres. At the center of the ARTEF is a hypobaric chamber which serves as a sealed atmospheric chamber for closed loop testing. A Human Metabolic Simulator (HMS) was custom-built to simulate the consumption of oxygen, and production of carbon dioxide, moisture and heat by up to eight persons. A variety of gas analyzers and dew point sensors are used to monitor the chamber atmosphere and the process flow upstream and downstream of a test article. A robust vacuum system is needed to simulate the vacuum of space.

Shortly after installation of the service and performance heat exchanger (SPCU HX) in 2001, samples collected from the coolant fluid indicated the presence of nickel accompanied by a subsequent decrease in phosphate concentration along with a high microbial load. When the SPCU HX was replaced and evaluated post-flight, it was expected that the heat exchanger would have significant biofilm and corrosion present given the composition of the coolant fluid; however, there was no evidence of either. Early results from two experiments imply that the heat exchanger materials themselves are inhibiting biofilm formation. This paper discusses the results of one set of experiments and puts forward the inhibition of quorum sensing as a possible mechanism for the lack of biofilm formation.

NASA's Digital Learning Network (DLN) reaches out to thousands of students each year through video conferencing and webcasting. As part of NASA's Strategic Plan to reach the next generation of space explorers, the DLN develops and delivers educational programs that reinforce principles in the areas of science, technology, engineering and mathematics. The DLN has created a series of live education videoconferences connecting the Desert Research and Technology Studies (RATS) field test to students across the United States. The programs are also extended to students around the world via live webcasting. The primary focus of the events is the Vision for Space Exploration. During the programs, Desert RATS engineers and scientists inform and inspire students about the importance of exploration and share the importance of the field test as it correlates with plans to return to the Moon and explore Mars. This paper describes the events that took place in September 2006.

Protecting astronauts from space radiation exposure is an important challenge for mission design and operations for future exploration-class and long-duration missions. Crew members are exposed to sporadic solar particle events (SPEs) as well as to the continuous galactic cosmic radiation (GCR). If sufficient protection is not provided the radiation risk to crew members from SPEs could be significant. To improve exposure risk estimates and radiation protection from SPEs, detailed evaluations of radiation shielding properties are required. A model using a modern CAD tool ProE™, which is the leading engineering design platform at NASA, has been developed for this purpose. For the calculation of radiation exposure at a specific site, the cosine distribution was implemented to replicate the omnidirectional characteristic of the 4π particle flux on a surface.

NASA's Digital Learning Network (DLN) reaches out to thousands of students each year through video conferencing and webcasting. The DLN has created a series of live education videoconferences connecting NASA's Extreme Environment Missions Operations (NEEMO) team to students across the United States. Programs are also extended to students around the world via live webcasting. The primary focus of the events is the vision for space exploration. During the programs, NEEMO crewmembers, including NASA astronauts, engineers and scientists, inform and inspire students about the importance of exploration and share the importance of the project as it correlates with plans to return to the moon and explore the planet Mars. These events highlight interactivity. Students talk live with the aquanauts in Aquarius, the National Oceanic and Atmospheric Administration's underwater laboratory located 4.5 kilometers off Key Largo in the Florida Keys National Marine Sanctuary.

Hamilton Sundstrand is under contract with the NASA Johnson Space Center to develop a scalable, evaporative heat rejection system called the Multi-Fluid Evaporator (MFE). It is being designed to support the Orion Crew Module and to support future Constellation missions. A MFE would be used from Earth sea level conditions to the vacuum of space. The current Space Shuttle configuration utilizes an ammonia boiler and flash evaporator system to achieve cooling at all altitudes. With the MFE system, both functions are combined into a single compact package with significant weight reduction and improved freeze-up protection. The heat exchanger core is designed so that radial flow of the evaporant provides increasing cross-sectional area to keep the back pressure low. Its multiple layer construction allows for efficient scale up to the desired heat rejection rate.