Search Results

Previously, a 10-year-old (YO) pediatric thorax finite element model (FEM) was developed and verified against child chest stiffness data measured from clinical cardiopulmonary resuscitation (CPR). However, the CPR experiments were performed at relatively low speeds, with a maximum loading rate of 250 mm/s. Studies showed that the biomechanical responses of human thorax exhibited rate sensitive characteristics. As such, the studies of dynamic responses of the pediatric thorax FEM are needed. Experimental pediatric cadaver data in frontal pendulum impacts and diagonal belt dynamic loading tests were used for dynamic validation. Thoracic force-deflection curves between test and simulation were compared. Strains predicted by the FEM and the injuries observed in the cadaver tests were also compared for injury assessment and analysis. This study helped to further improve the 10 YO pediatric thorax FEM.

As early as the 1950's, Gurdjian and colleagues (Gurdjian et al., 1955) observed that brain injuries could occur by direct pressure loading without any global head accelerations. This pressure-induced injury mechanism was "forgotten" for some time and is being rekindled due to the many mild traumatic brain injuries attributed to blast overpressure. The aim of the current study was to develop a finite element (FE) model to predict the biomechanical response of rat brain under a shock tube environment. The rat head model, including more than 530,000 hexahedral elements with a typical element size of 100 to 300 microns was developed based on a previous rat brain model for simulating a blunt controlled cortical impact. An FE model, which represents gas flow in a 0.305-m diameter shock tube, was formulated to provide input (incident) blast overpressures to the rat model. It used an Eulerian approach and the predicted pressures were verified with experimental data.

Complete validation of any finite element (FE) model of the human brain is very difficult due to the lack of adequate experimental data. However, more animal brain injury data, especially rat data, obtained under well-defined mechanical loading conditions, are available to advance the understanding of the mechanisms of traumatic brain injury. Unfortunately, internal response of the brain in these experimental studies could not be measured. The aim of this study was to develop a detailed FE model of the rat brain for the prediction of intracranial responses due to different impact scenarios. Model results were used to elucidate possible brain injury mechanisms. An FE model, consisting of more than 250,000 hexahedral elements with a typical element size of 100 to 300 microns, was developed to represent the brain of a rat. The model was first validated locally against peak brain deformation data obtained from nine unique dynamic cortical deformation (vacuum) tests.