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Previously, a 10-year-old (YO) pediatric thorax finite element model (FEM) was developed and verified against child chest stiffness data measured from clinical cardiopulmonary resuscitation (CPR). However, the CPR experiments were performed at relatively low speeds, with a maximum loading rate of 250 mm/s. Studies showed that the biomechanical responses of human thorax exhibited rate sensitive characteristics. As such, the studies of dynamic responses of the pediatric thorax FEM are needed. Experimental pediatric cadaver data in frontal pendulum impacts and diagonal belt dynamic loading tests were used for dynamic validation. Thoracic force-deflection curves between test and simulation were compared. Strains predicted by the FEM and the injuries observed in the cadaver tests were also compared for injury assessment and analysis. This study helped to further improve the 10 YO pediatric thorax FEM.

Commotio Cordis (CC) is the second leading cause of mortality in youth sports. Impacts occurring directly over the left ventricle (LV) during a vulnerable period of the cardiac cycle can cause ventricular fibrillation (VF), which results in CC. In order to better understand the pathophysiology of CC, and develop a mechanical model for CC, appropriate injury criteria need to be developed. This effort consisted of impacts to seventeen juvenile porcine specimens (mass 21-45 kg). Impacts were delivered over the cardiac silhouette during the venerable period of the cardiac cycle. Four impact speeds were used: 13.4, 17.9, 22.4, and 26.8 m/s. The impactor was a lacrosse ball on an aluminum shaft instrumented with an accelerometer (mass 188 g - 215 g). The impacts were recorded using high-speed video. LV pressure was measured with a catheter. Univariate binary logistic regression analyses were performed to evaluate the predictive ability of ten injury criteria.

As early as the 1950's, Gurdjian and colleagues (Gurdjian et al., 1955) observed that brain injuries could occur by direct pressure loading without any global head accelerations. This pressure-induced injury mechanism was "forgotten" for some time and is being rekindled due to the many mild traumatic brain injuries attributed to blast overpressure. The aim of the current study was to develop a finite element (FE) model to predict the biomechanical response of rat brain under a shock tube environment. The rat head model, including more than 530,000 hexahedral elements with a typical element size of 100 to 300 microns was developed based on a previous rat brain model for simulating a blunt controlled cortical impact. An FE model, which represents gas flow in a 0.305-m diameter shock tube, was formulated to provide input (incident) blast overpressures to the rat model. It used an Eulerian approach and the predicted pressures were verified with experimental data.

In present GDI engines, multiple injection strategies are often employed for engine cold start mixture formation. In the future, these strategies may also be used to control the combustion process, and to prevent misfiring or high emission levels. While the processes occurring during individual injections of GDI injectors have been investigated by a number of researchers, this paper concentrates on the interactions of multiple injection events. Even though multiple injection strategies are already applied in most GDI engines, the impact of the first injection event on the second injection event has not been analyzed in detail yet. Different optical measurement techniques are used in order to investigate the interaction of the two closely timed injection events, as well as the effect of dwell time and the in-cylinder conditions. The injector investigated is a GDI piezo injector with an outwardly opening needle.

The pia-arachnoid complex (PAC) covering the brain plays an important role in the mechanical response of the brain due to impact or inertial loading. However, the mechanical properties of the pia-arachnoid complex and its influence on the overall response of the brain have not been well characterized. Consequently, finite element (FE) brain models have tended to oversimplify the response of the pia-arachnoid complex, possibly resulting in a loss of accuracy in the model predictions. The aim of this study was to determine, experimentally, the material properties of the pia-arachnoid complex under quasi-static and dynamic loading conditions. Specimens of the pia-arachnoid complex were obtained from the parietal and temporal regions of freshly slaughtered bovine subjects with the specimen orientation recorded. Single-stroke, uniaxial quasi-static and dynamic tensile experiments were performed at strain-rates of 0.05, 0.5, 5 and 100 s-1 (n = 10 for each strain rate group).

Traumatic brain injury (TBI) continues to be a major health problem, with over 500,000 cases per year with a societal cost of approximately $85 billion in the US. Motor vehicle accidents are the leading cause of such injuries. In many cases of TBI widespread disruption of the axons occurs through a process known as diffuse axonal injury (DAI) or traumatic axonal injury (TAI). In the current study, an in vivo TAI model was developed using spinal nerve roots of adult rats. This model was used to determine functional and structural responses of axons to various strains and displacement rates. Fifty-six L5 dorsal nerve roots were each subjected to a predetermined strain range (<10%, 10-20% and >20%) at a specified displacement rate (0.01 mm/sec and 15 mm/sec) only once. Image analysis was used to determine actual strains on the roots during the pull.

Complete validation of any finite element (FE) model of the human brain is very difficult due to the lack of adequate experimental data. However, more animal brain injury data, especially rat data, obtained under well-defined mechanical loading conditions, are available to advance the understanding of the mechanisms of traumatic brain injury. Unfortunately, internal response of the brain in these experimental studies could not be measured. The aim of this study was to develop a detailed FE model of the rat brain for the prediction of intracranial responses due to different impact scenarios. Model results were used to elucidate possible brain injury mechanisms. An FE model, consisting of more than 250,000 hexahedral elements with a typical element size of 100 to 300 microns, was developed to represent the brain of a rat. The model was first validated locally against peak brain deformation data obtained from nine unique dynamic cortical deformation (vacuum) tests.

Cerebral blood vessels are an integral part of the brain and may play a role in the response of the brain to impact. The purpose of this study was to quantify the effects of surrogate vessels on the deformation patterns of a physical model of the brain under various impact conditions. Silicone gel and tubing were used as surrogates for brain tissue and blood vessels, respectively. Two aluminum cylinders representing a coronal section of the brain were constructed. One cylinder was filled with silicone gel only, and the other was filled with silicone gel and silicone tubing arranged in the radial direction in the peripheral region. An array of markers was embedded in the gel in both cylinders to facilitate strain calculation via high-speed video analysis. Both cylinders were simultaneously subjected to a combination of linear and angular acceleration using a two-segment pendulum.

Lower extremity injuries in frontal automotive crashes usually occur with footwell intrusion where both the knee and foot are constrained. In order to identify factors associated with tibial shaft injury, a series of numerical simulations were conducted using a finite element model of the whole human body. These simulations demonstrated that tibial mid-shaft injuries in frontal crashes could be caused by an abrupt change in velocity and a high rate of footwell intrusion.

The purposes of this study were to measure the relative linear and angular displacements of each pair of adjacent cervical vertebrae and to compute changes in distance between two adjacent facet joint landmarks during low posterior- anterior (+Gx) acceleration without significant hyperextension of the head. A total of twenty-six low speed rear-end impacts were conducted using six postmortem human specimens. Each cadaver was instrumented with two to three neck targets embedded in each cervical vertebra and nine accelerometers on the head. Sequential x-ray images were collected and analyzed. Two seatback orientations were studied. In the global coordinate system, the head, the cervical vertebrae, and the first or second thoracic vertebra (T1 or T2) were in extension during rear-end impacts. The head showed less extension in comparison with the cervical spine.

Previous studies have hypothesized that the shoulder may be used to absorb some impact energy and reduce chest injury due to side impacts. Before this hypothesis can be tested, a good understanding of the injury mechanisms and the kinematics of the shoulder is critical for occupant protection in side impact. However, existing crash dummies and numerical models are not designed to reproduce the kinematics and kinetics of the human shoulder. The purpose of this study was to develop a finite element model of the human shoulder in order to achieve a deeper understanding of the injury mechanisms and the kinematics of the shoulder in side impact. Basic anthropometric data of the human shoulder used to develop the skeletal and muscular portions of this model were taken from commercial data packages. The shoulder model included three bones (the humerus, scapula and clavicle) and major ligaments and muscles around the shoulder.

Finite element models of human body segments have been developed in recent years. Numerical simulation could be helpful when understanding injury mechanisms and to make injury assessments. In the lower leg injury research in NISSAN, a finite element model of the human ankle/foot is under development. The mesh for the bony part was taken from the original model developed by Beaugonin et al., but was revised by adding soft tissue to reproduce realistic responses. Damping effect in a high speed contact was taken into account by modeling skin and fat in the sole of the foot. The plantar aponeurosis tendon was modeled by nonlinear bar elements connecting the phalanges to the calcaneus. The rigid body connection, which was defined at the toe in the original model for simplicity, was removed and the transverse ligaments were added instead in order to bind the metatarsals and the phalanges. These tendons and ligaments were expected to reproduce a realistic response in compression.

Relative motion between the brain and skull may explain many types of brain injury such as intracerebral hematomas due to bridging veins rupture [1] and cerebral contusions. However, no experimental methods have been developed to measure the magnitude of this motion. Consequently, relative motion between the brain and skull predicted by analytical tools has never been validated. In this study, radio opaque markers were placed in the skull and neutral density markers were placed in the brain in two vertical columns in the occipitoparietal and temporoparietal regions. A bi-planar, high-speed x-ray system was used to track the motion of these markers. Due to limitations in current technology to record the x-ray image on high-speed video cameras, only low- speed (﹤ 4m/s) impact data were available.

The purpose of this study is to help understand the thoracic response and injury mechanisms in high-energy, limited-stroke, lateral velocity pulse impacts to the human chest wall. To impart such impacts, a linear impactor was developed which had a limited stroke and minimally decreased velocity during impact. The peak impact velocity was 5.6 ± 0.3 m/s. A series of BioSID and cadaver tests were conducted to measure biomechanical response and injury data. The conflicting effects of padding on increased deflection and decreased acceleration were demonstrated in tests with BioSID and cadavers. The results of tests conducted on six cadavers were used to test several proposed injury criteria for side impact. Linear regression was used to correlate each injury criterion to the number of rib fractures. This test methodology captured and supported a contrasting trend of increased chest deflection and decreased TTI when padding was introduced.

Although not life threatening in most cases, victims of lower extremity injuries frequently end up living with a poor quality of life. The implementations of airbag supplement restraint systems significantly reduce the incidence of head and chest injuries. However, the frequency of leg injuries remains high. Several finite element models of the foot and ankle have been developed to further the understanding of this injury mechanism. None of those models employed accurate geometry among various bony segments. The objective of this study is to develop a foot and ankle finite element model based on CT scan data so that joint geometry can be accurately represented. The model was validated against experimental data for several different configurations including typical car crash situations.

Ten pairs of thawed fresh-frozen human cadaveric lower arm specimens were subjected to lateral three-point bending. Either the radius or ulna were impacted with a 4.5 kg dropped weight at approximately 3 m/s or tested quasi-statically in a materials testing machine. Fracture occurred primarily near the loading site with an average dynamic peak load of 1370 N and average peak moment of 89 Nm. Differences between the radius and ulna were not significant. Static fracture load and moments were approximately 20% lower. Sectional and mineral properties of each specimen near the fracture sites were measured.

Numerical analyses of head and neck response during side impact are presented in this paper. A mathematical human model for side impact simulation was developed based on previous studies of other researchers. The effects of muscular activities during severe side impact were analyzed with the use of this model. This study shows that the effect of muscular activities is significant especially if the occupant is prepared to resist the impact. This result suggests that the modeling of muscles is important for the simulation of real accident situation.

A three-dimensional finite element model of a human neck has been developed in an effort to study the mechanics of cervical spine while subjected to impacts. The neck geometry was obtained from MRI scans of a 50th percentile male volunteer. This model, consisting of the vertebrae from C1 through T1 including the intervertebral discs and posterior elements, was constructed primarily of 8-node brick elements. The vertebrae were modeled using linear elastic-plastic materials, while the intervertebral discs were modeled using linear viscoelastic materials. Sliding interfaces were defined to simulate the motion of synovial facet joints. Anterior and posterior longitudinal ligaments, facet joint capsular ligaments, alar ligaments, transverse ligaments, and anterior and posterior atlanto-occipital membranes were modeled as nonlinear bar elements or as tension-only membrane elements. A previously developed head and brain model was also incorporated.

The mechanisms of knee fracture were studied experimentally using cadaveric knees and analytically by computer simulation. Ten 90 degree flexed knees were impacted frontally by a 20 kg pendulum with a rigid surface, a 450 psi (3.103 MPa) crush strength and a 100 psi (0.689 MPa) crush strength aluminum honeycomb padding and a 50 psi (0.345 MPa) crush strength paper honeycomb padding at a velocity of about five m/s. During rigid surface impact, a patella fracture and a split condylar fracture were observed. The split condylar fracture was generated by the patella pushing the condyles apart, based on a finite element model using the maximum principal stress as the injury criterion. In the case of the 450 psi aluminum honeycomb padding, the split condylar fracture still occurred, but no patella fractures were observed because the honeycomb provided a more uniform distribution of patella load. No bony fractures in the knee area occurred for impacts with a 50 psi paper honeycomb padding.

A humerus provisional reference value (PRV) based on human surrogate data was developed to help evaluate upper arm injury potential. The proposed PRV is based on humerus bone bending moments generated by testing pairs of cadaver arms to fracture in three-point bending on an Instron testing machine in either lateral-medial (L-M) or anterior-posterior (A-P) loading, at 218 mm/s and 0.635 mm/s loading rates. The results were then normalized and scaled to 50th and 5th percentile sized occupants. The normalized average L-M bending moment at failure test result was 6 percent more than the normalized average A-P bending moment. The normalized average L-M shear force at failure was 23 percent higher than the normalized average A-P shear force. The faster rate of loading resulted in a higher average bending moment overall - 8 percent in the L-M and 14 percent in the A-P loading directions.