Search Results

As early as the 1950's, Gurdjian and colleagues (Gurdjian et al., 1955) observed that brain injuries could occur by direct pressure loading without any global head accelerations. This pressure-induced injury mechanism was "forgotten" for some time and is being rekindled due to the many mild traumatic brain injuries attributed to blast overpressure. The aim of the current study was to develop a finite element (FE) model to predict the biomechanical response of rat brain under a shock tube environment. The rat head model, including more than 530,000 hexahedral elements with a typical element size of 100 to 300 microns was developed based on a previous rat brain model for simulating a blunt controlled cortical impact. An FE model, which represents gas flow in a 0.305-m diameter shock tube, was formulated to provide input (incident) blast overpressures to the rat model. It used an Eulerian approach and the predicted pressures were verified with experimental data.

The pia-arachnoid complex (PAC) covering the brain plays an important role in the mechanical response of the brain due to impact or inertial loading. The mechanical properties of the bovine PAC under tensile loading have been characterized previously. However, the transverse properties of this structure, such as shear and normal traction which are equally important to understanding the skull/brain interaction under traumatic loading, have not been investigated. These material properties are essential information needed to adequately define the material model of the PAC in a finite element (FE) model of human brain. The purpose of this study was to determine, experimentally, the material properties of the PAC under normal traction loading. PAC specimens were obtained from freshly slaughtered bovine subjects from various locations.

High-speed biplane x-ray and neutral density targets were used to examine brain displacement and deformation during impact. Relative motion, maximum principal strain, maximum shear strain, and intracranial pressure were measured in thirty-five impacts using eight human cadaver head and neck specimens. The effect of a helmet was evaluated. During impact, local brain tissue tends to keep its position and shape with respect to the inertial frame, resulting in relative motion between the brain and skull and deformation of the brain. The local brain motions tend to follow looping patterns. Similar patterns are observed for impact in different planes, with some degree of posterior-anterior and right-left symmetry. Peak coup pressure and pressure rate increase with increasing linear acceleration, but coup pressure pulse duration decreases. Peak average maximum principal strain and maximum shear are on the order of 0.09 for CFC 60 Hz data for these tests.

This study characterizes the response of the human cadaver abdomen to high-speed seatbelt loading using pyrotechnic pretensioners. A test apparatus was developed to deliver symmetric loading to the abdomen using a seatbelt equipped with two low-mass load cells. Eight subjects were tested under worst-case scenario, out-of-position (OOP) conditions. A seatbelt was placed at the level of mid-umbilicus and drawn back along the sides of the specimens, which were seated upright using a fixed-back configuration. Penetration was measured by a laser, which tracked the anterior aspect of the abdomen, and by high-speed video. Additionally, aortic pressure was monitored. Three different pretensioner designs were used, referred to as system A, system B and system C. The B and C systems employed single pretensioners. The A system consisted of two B system pretensioners. The vascular systems of the subjects were perfused.

The pia-arachnoid complex (PAC) covering the brain plays an important role in the mechanical response of the brain due to impact or inertial loading. However, the mechanical properties of the pia-arachnoid complex and its influence on the overall response of the brain have not been well characterized. Consequently, finite element (FE) brain models have tended to oversimplify the response of the pia-arachnoid complex, possibly resulting in a loss of accuracy in the model predictions. The aim of this study was to determine, experimentally, the material properties of the pia-arachnoid complex under quasi-static and dynamic loading conditions. Specimens of the pia-arachnoid complex were obtained from the parietal and temporal regions of freshly slaughtered bovine subjects with the specimen orientation recorded. Single-stroke, uniaxial quasi-static and dynamic tensile experiments were performed at strain-rates of 0.05, 0.5, 5 and 100 s-1 (n = 10 for each strain rate group).

Complete validation of any finite element (FE) model of the human brain is very difficult due to the lack of adequate experimental data. However, more animal brain injury data, especially rat data, obtained under well-defined mechanical loading conditions, are available to advance the understanding of the mechanisms of traumatic brain injury. Unfortunately, internal response of the brain in these experimental studies could not be measured. The aim of this study was to develop a detailed FE model of the rat brain for the prediction of intracranial responses due to different impact scenarios. Model results were used to elucidate possible brain injury mechanisms. An FE model, consisting of more than 250,000 hexahedral elements with a typical element size of 100 to 300 microns, was developed to represent the brain of a rat. The model was first validated locally against peak brain deformation data obtained from nine unique dynamic cortical deformation (vacuum) tests.

Numerical analyses frequently accompany experimental investigations that study injury biomechanics and improvements in automotive safety. Limited by computational speed, earlier mathematical models tended to simplify the system under study so that a set of differential equations could be written and solved. Advances in computing technology and analysis software have enabled the development of many sophisticated models that have the potential to provide a more comprehensive understanding of human impact response, injury mechanisms, and tolerance. In this article, 50 years of publications on numerical modeling published in the Stapp Car Crash Conference Proceedings and Journal were reviewed. These models were based on: (a) author-developed equations and software, (b) public and commercially available programs to solve rigid body dynamic models (such as MVMA2D, CAL3D or ATB, and MADYMO), and (c) finite element models.

Although biomechanical studies on the knee-thigh-hip (KTH) complex have been extensive, interactions between the KTH and various vehicular interior design parameters in frontal automotive crashes for newer models have not been reported in the open literature to the best of our knowledge. A 3D finite element (FE) model of a 50th percentile male KTH complex, which includes explicit representations of the iliac wing, acetabulum, pubic rami, sacrum, articular cartilage, femoral head, femoral neck, femoral condyles, patella, and patella tendon, has been developed to simulate injuries such as fracture of the patella, femoral neck, acetabulum, and pubic rami of the KTH complex. Model results compared favorably against regional component test data including a three-point bending test of the femur, axial loading of the isolated knee-patella, axial loading of the KTH complex, axial loading of the femoral head, and lateral loading of the isolated pelvis.

Several three-dimensional (3D) finite element (FE) models of the human body have been developed to elucidate injury mechanisms due to automotive crashes. However, these models are mainly focused on 50th percentile male. As a first step towards a better understanding of injury biomechanics in the small female, a 3D FE model of a 5th percentile female human chest (FEM-5F) has been developed and validated against experimental data obtained from two sets of frontal impact, one set of lateral impact, two sets of oblique impact and a series of ballistic impacts. Two previous FE models, a small female Total HUman Model for Safety (THUMS-AF05) occupant version 1.0ϐ (Kimpara et al., 2002) and the Wayne State University Human Thoracic Model (WSUHTM, Wang 1995 and Shah et al., 2001) were integrated and modified for this model development.

Knee injuries represent about 10% of all injuries suffered during car crashes. Efforts to assess the injury risk to the posterior cruciate ligament (PCL) have been based on a study available in the literature (Viano et al., 1978), in which only two of the five knees tested had PCL ruptures. The aims of the current study were to repeat the study with a higher number of samples, study the effects of other soft tissues on knee response, and assess the adequacy of the experimental setup for the identification of a PCL tolerance. A total of 14 knees were tested using a high-speed materials testing machine. Eight were intact knees (with the patella and all the muscular and ligamentous structures), three were PCL-only knees (patella and all the muscular and ligamentous structures other than the PCL removed), and the last three were PCL-only knees with the tibia protected from bending fracture.

Cerebral blood vessels are an integral part of the brain and may play a role in the response of the brain to impact. The purpose of this study was to quantify the effects of surrogate vessels on the deformation patterns of a physical model of the brain under various impact conditions. Silicone gel and tubing were used as surrogates for brain tissue and blood vessels, respectively. Two aluminum cylinders representing a coronal section of the brain were constructed. One cylinder was filled with silicone gel only, and the other was filled with silicone gel and silicone tubing arranged in the radial direction in the peripheral region. An array of markers was embedded in the gel in both cylinders to facilitate strain calculation via high-speed video analysis. Both cylinders were simultaneously subjected to a combination of linear and angular acceleration using a two-segment pendulum.

The purpose of this study was to determine the effect of head-neck position on cervical facet stretch during low speed rear end impact. Twelve tests were conducted on four Post Mortem Human Subjects (PMHS) in a generic bucket seat environment. Three head positions, namely Normal (neutral), Zero Clearance between the head and head restraint, and Body Forward positions were tested. A high-speed x-ray system was used to record the motion of cervical vertebrae during these tests. Results demonstrate that: a) The maximum mean facet stretch at head restraint contact occurs at MS4 and MS5 for the Body Forward condition, b) The lower neck flexion moment, prior to head contact, shows a non-linear relationship with facet stretch, and c) “Differential rebound” during rear end impact increases facet stretch.

Little has been reported in the literature on the compressive properties of muscle. These data are needed for the development of finite element models that address impact of the muscles, especially in the study of pedestrian impact. Tests were conducted to characterize the compressive response of muscle. Volunteers, cadaveric specimens and a Hybrid III dummy were impacted in the posterior and lateral aspect of the lower leg using a free flying pendulum. Volunteer muscles were tested while tensed and relaxed. The effects of muscle tension were found to influence results, especially in posterior leg impacts. Cadaveric response was found to be similar to that of the relaxed volunteer. The resulting data can be used to identify a material law using an inverse method.

Typical automotive related abdominal injuries occur due to contact with the rim of the steering wheel, seatbelt and armrest, however, the rate is less than in other body regions. When solid abdominal organs, such as the liver, kidneys and spleen are involved, the injury severity tends to be higher. Although sled and pendulum impact tests have been conducted using cadavers and animals, the mechanical properties and the tissue level injury tolerance of abdominal solid organs are not well characterized. These data are needed in the development of computer models, the improvement of current anthropometric test devices and the enhancement of our understanding of abdominal injury mechanisms. In this study, a series of experimental tests on solid abdominal organs was conducted using porcine liver, kidney and spleen specimens. Additionally, the injury tolerance of the solid organs was deduced from the experimental data.

Brain tissue architecture consists of a complex network of neurons and vasculature interspersed within a matrix of supporting cells. The role of the relatively suffer blood vessels on the more compliant brain tissues during rapid loading has not been properly investigated. Two 2-D finite element models of the human head were developed. The basic model (Model I) consisted of the skull, dura matter, cerebral spinal fluid (CSF), tentorium, brain tissue and the parasagittal bridging veins. The pia mater was also included but in a simplified form which does not correspond to the convolutions of the brain. In Model II, major branches of the cerebral arteries were added to Model I. Material properties for the brain tissues and vasculature were taken from those reported in the literature. The model was first validated against intracranial pressure and brain/skull relative motion data from cadaveric tests.

Aortic injuries during blunt thoracic impacts can lead to life threatening hemorrhagic shock and potential exsanguination. Experimental approaches designed to study the mechanism of aortic rupture such as the testing of cadavers is not only expensive and time consuming, but has also been relatively unsuccessful. The objective of this study was to develop a computer model and to use it to predict modes of loading that are most likely to produce aortic ruptures. Previously, a 3D finite element model of the human thorax was developed and validated against data obtained from lateral pendulum tests. The model included a detailed description of the heart, lungs, rib cage, sternum, spine, diaphragm, major blood vessels and intercostal muscles. However, the aorta was modeled as a hollow tube using shell elements with no fluid within, and its material properties were assumed to be linear and isotropic.

The Lower Limb Model for Safety (LLMS) is a finite element model of the lower limb developed mainly for safety applications. It is based on a detailed description of the lower limb anatomy derived from CT and MRI scans collected on a subject close to a 50th percentile male. The main anatomical structures from ankle to hip (excluding the hip) were all modeled with deformable elements. The modeling of the foot and ankle region was based on a previous model Beillas et al. (1999) that has been modified. The global validation of the LLMS focused on the response of the isolated lower leg to axial loading, the response of the isolated knee to frontal and lateral impact, and the interaction of the whole model with a Hybrid III model in a sled environment, for a total of nine different set-ups. In order to better characterize the axial behavior of the lower leg, experiments conducted on cadaveric tibia and foot were reanalyzed and experimental corridors were proposed.

Many finite element models have been developed by several research groups in order to achieve a better understanding of brain injury. Due to the lack of experimental data, validation of these models has generally been limited. Consequently, applying these models to investigate brain responses has also been limited. Over the last several years, several versions of the Wayne State University brain injury model (WSUBIM) were developed. However, none of these models is capable of simulating indirect impacts with an angular acceleration higher than 8,000 rad/s2. Additionally, the density and quality of the mesh in the regions of interest are not detailed and sensitive enough to accurately predict the stress/strain level associated with a wide range of impact severities. In this study, WSUBIM version 2001, capable of simulating direct and indirect impacts with a combined translational and rotational acceleration of the head up to 200 g and 12,000 rad/s2 has been developed.

The principal focus of this study was the measurement of relative brain motion with respect to the skull using a high-speed, biplanar x-ray system and neutral density targets (NDTs). A suspension fixture was used for testing of inverted, perfused, human cadaver heads. Each specimen was subjected to multiple tests, either struck at rest using a 152-mm-diameter padded impactor face, or stopped against an angled surface from steady-state motion. The impacts were to the frontal and occipital regions. An array of multiple NDTs was implanted in a double-column scheme of 5 and 6 targets, with 10 mm between targets in each column and 80 mm between columns. These columns were implanted in the temporoparietal and occipitoparietal regions. The impacts produced peak resultant accelerations of 10 to 150 g, and peak angular accelerations between 1000 and 8000 rad/s2. For all but one test, the peak angular speeds ranged from 17 to 22 rad/s.

The purposes of this study were to measure the relative linear and angular displacements of each pair of adjacent cervical vertebrae and to compute changes in distance between two adjacent facet joint landmarks during low posterior- anterior (+Gx) acceleration without significant hyperextension of the head. A total of twenty-six low speed rear-end impacts were conducted using six postmortem human specimens. Each cadaver was instrumented with two to three neck targets embedded in each cervical vertebra and nine accelerometers on the head. Sequential x-ray images were collected and analyzed. Two seatback orientations were studied. In the global coordinate system, the head, the cervical vertebrae, and the first or second thoracic vertebra (T1 or T2) were in extension during rear-end impacts. The head showed less extension in comparison with the cervical spine.