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Turbulent combustion modeling in a RANS or LES context imposes the challenge of closing the chemical reaction rate on the sub-grid level. Such turbulent models have as their two main ingredients sources from chemical reactions and turbulence-chemistry interaction. The various combustion models then differ mainly by how the chemistry is calculated (level of detail, canonical flame model) and on the other hand how turbulence is assumed to affect the reaction rate on the sub-grid level (TCI - turbulence-chemistry interaction). In this work, an advanced combustion model based on tabulated chemistry is applied for 3D CFD (computational fluid dynamics) modeling of Diesel engine cases. The combustion model is based on the FGM (Flamelet Generated Manifold) chemistry reduction technique. The underlying chemistry tabulation process uses auto-ignition trajectories of homogeneous fuel/air mixtures, which are computed with detailed chemical reaction mechanisms.