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After launch and activation activities, the Columbus module started its operational life on February 2008 providing resources to the internal and external experiments. In March 2008 two US Payloads were successfully installed into Columbus Module: Microgravity Sciences Glovebox (MSG) and a US payload of the Express rack family, Express Rack 3, carrying the European Modular Cultivation System (EMCS) experiment. They were delivered to the European laboratory from the US laboratory and followed few months later by similar racks; Human Research Facility 1 (HRF1) and HRF2. The following paper provides an overview of US Payloads, giving their main features and experiments run inside Columbus on year 2008. Flight issues, mainly on the hydraulic side are also discussed. Engineering evaluations released to the flight control team, telemetry data, and relevant mathematical models predictions are described providing a background material for the adopted work-around solutions.

ESA and NASA agencies agreed to run an interface compatibility test at the EADS facility between the Columbus flight module and a duplicate ground unit of a currently on-orbit US International Standard Payload Rack, the Human Research Facility (HRF) Flight Prototype Rack (FPR). The purpose of the test was to demonstrate the capability to run US payloads inside the European ISS module Columbus. One of the critical aspects to be verified to ensure suitable operations of the two systems was the combined performance of the hydraulic controls resident in the HRF and Columbus coolant loops. A hydraulic model of the HRF FPR was developed and combined with the Columbus Active Thermal Control System (ATCS) model. Several coupled thermal-hydraulic test cases were then performed, preceded by mathematical analysis, required to predict safe test conditions and to optimize the Columbus valve configurations.