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The Columbus laboratory module for the International Space Station (ISS) uses active thermal control for cooling of avionics and payload in the pressurized compartment. The Active Thermal Control Subsystem (ATCS) is based on a water loop rejecting waste heat to the Medium Temperature Heat Exchanger and Low Temperature Heat Exchanger on Node 2, part of the US Segment of the ISS. Flow and temperature control in the ATCS is achieved by means of the Water Pump Assembly (WPA) and the 3-Way Modulating Valve (WTMO) units. For the flow control the WPA speed is commanded so that a fixed pressure drop is maintained over the plenum with the avionics and payload branches. Adjusting the WTMO internal flow split permit the two active units to perform the CHX and plenum inlet temperature control. The WPA includes a filter and an accumulator to control the pressure in the ATCS and to compensate for leakage and temperature-dependent volume variations.

ESA and NASA agencies agreed to run an interface compatibility test at the EADS facility between the Columbus flight module and a duplicate ground unit of a currently on-orbit US International Standard Payload Rack, the Human Research Facility (HRF) Flight Prototype Rack (FPR). The purpose of the test was to demonstrate the capability to run US payloads inside the European ISS module Columbus. One of the critical aspects to be verified to ensure suitable operations of the two systems was the combined performance of the hydraulic controls resident in the HRF and Columbus coolant loops. A hydraulic model of the HRF FPR was developed and combined with the Columbus Active Thermal Control System (ATCS) model. Several coupled thermal-hydraulic test cases were then performed, preceded by mathematical analysis, required to predict safe test conditions and to optimize the Columbus valve configurations.