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To address the growing need for detailed chemistry in engine simulations, new software tools and validated data sets are being developed under an industry-funded consortium involving members from the automotive and fuels industry. The results described here include systematic comparison and validation of detailed chemistry models using a wide range of fundamental experimental data, and the development of software tools that support the use of detailed mechanisms in engineering simulations. Such tools include the automated reduction of reaction mechanisms for targeted simulation conditions. Selected results are presented and discussed.