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After several decades of human spaceflight, the community of space-faring nations has accumulated a diverse and sometimes harrowing history of toxicological events that have plagued human space endeavors almost from the very beginning. Some lessons have been learned in ground-based test beds and others were discovered the hard way - when human lives were at stake in space. From such lessons one can build a risk-management framework for toxicological events to minimize the probability of a harmful exposure, while recognizing that we cannot predict all possible events. Space toxicologists have learned that relatively harmless compounds can be converted by air revitalization systems into compounds that cause serious harm to the crew.

A set of devices for measurement of human balance orientation and eye movements in weightlessness was developed for neurovestibular experiments on Spacelab. The experiments involve astronaut motion, limb position changes, and moving visual fields, measurements are made of eye movements, muscular activity and orientation perception. This joint US/Canadian research program represent a group of closely related experiments designed to investigate space motion sickness, any associated changes in otolith-mediated responses occurring during weightlessness, and the continuation of changes to postflight conditions. The otoliths are a component of the vestibular apparatus which is located in the middle ear. It is responsible for maintaining the body's balance. Gravitational pull on the otoliths causes them to constantly appraise the nervous system of the position of the head with respect to the direction of gravity.

An integrated water recovery system was operated for 91 days in support of the Lunar Mars Life Support Test Project (LMLSTP) Phase III test. The system combined both biological and physical-chemical processes to treat a combined wastewater stream consisting of waste hygiene water, urine, and humidity condensate. Biological processes were used for primary degradation of organic material as well as for nitrification of ammonium in the wastewater. Physical-chemical systems removed inorganic salts from the water and provided post-treatment. The integrated system provided potable water to the crew throughout the test. This paper describes the water recovery system and reviews the performance of the system during the test.

Recovery of potable water from wastewater is essential for the success of long-term manned missions to the moon and Mars. Honeywell International and the team consisting of Thermodistillation Company (Kyiv, Ukraine) and NASA Johnson Space Center (JSC) Crew and Thermal Systems Division are developing a wastewater processing subsystem that is based on centrifugal vacuum distillation. The Wastewater Processing Cascade Distillation Subsystem (CDS) utilizes an innovative and efficient multi-stage thermodynamic process to produce purified water. The rotary centrifugal design of the system also provides gas/liquid phase separation and liquid transport under microgravity conditions. A five-stage prototype of the subsystem was built, delivered and integrated into the NASA JSC Advanced Water Recovery Systems Development Facility for development testing.

The aim of this study was to explore if fingernail delamination injury following EMU glove use may be caused by compression-induced blood flow occlusion in the finger. During compression tests, finger blood flow decreased more than 60%, however this occurred more rapidly for finger pad compression (4 N) than for fingertips (10 N). A pressure bulb compression test resulted in 50% and 45% decreased blood flow at 100 mmHg and 200 mmHg, respectively. These results indicate that the finger pad pressure required to articulate stiff gloves is more likely to contribute to injury than the fingertip pressure associated with tight fitting gloves.

The Equivalent System Mass (ESM) metric developed by NASA describes and compares individual system impact on a closed system in terms of a single parameter, mass. The food system of a Mars mission may encompass a large percentage of total mission ESM, and decreasing this ESM would be beneficial. Yeast breads were made using three methods (hand & oven, bread machine, mixer with dough hook attachment & oven). Flat breads were made using four methods (hand & oven, hand & griddle, mixer with dough hook attachment & oven, mixer with dough hook attachment & griddle). Two formulations were used for each bread system (scratch ingredients, commercial mix). ESM was calculated for each of these scenarios. The objective of this study was to compare the ESM of yeast and flat bread production for a Martian surface outpost. Method (equipment) for both types of bread production was demonstrated to be the most significant influence of ESM when one equipment use was assumed.

The work presented in this paper summarizes the early results of an integrated advanced water recovery system test conducted by the Crew and Thermal Systems Division (CTSD) at NASA-Johnson Space Center (JSC). The system design and the results of the first two months of operation are presented. The overall objective of this test is to demonstrate the capability of an integrated advanced water recovery system to produce potable quality water for at least six months. Each subsystem is designed for operation in microgravity. The primary treatment system consists of a biological system for organic carbon and ammonia removal. Dissolved solids are removed by reverse osmosis and air evaporation systems. Finally, ion exchange technology in combination with photolysis or photocatalysis is used for polishing of the effluent water stream. The wastewater stream consists of urine and urine flush water, hygiene wastewater and a simulated humidity condensate.

The International Space Station Waste Collector Subsystem Risk Mitigation Experiment (ISS WCS RME) was flown as the primary (Shuttle) WCS on Space Shuttle flight STS-104 (ISS-7A) in July 2001, to validate new design enhancements. In general, the WCS is utilized for collecting, storing, and compacting fecal & associated personal hygiene waste, in a zero gravity environment. In addition, the WCS collects and transfers urine to the Shuttle waste storage tank. All functions are executed while controlling odors and providing crew comfort. The ISS WCS previously flew on three Shuttle flights as the Extended Duration Orbiter (EDO) WCS, as it was originally designed to support extended duration Space Shuttle flights up to 30 days in length. Soon after its third flight, the Space Shuttle Program decided to no longer require 30 day extended mission duration capability and provided the EDO WCS to the ISS Program.

This paper presents the results of a study of how people interacted with a production voice-command based interface while driving on public roadways. Tasks included phone contact calling, full address destination entry, and point-of-interest (POI) selection. Baseline driving and driving while engaging in multiple-levels of an auditory-vocal cognitive reference task and manual radio tuning were used as comparison points. Measures included self-reported workload, task performance, physiological arousal, glance behavior, and vehicle control for an analysis sample of 48 participants (gender balanced across ages 21-68). Task analysis and glance measures confirm earlier findings that voice-command interfaces do not always allow the driver to keep their hands on the wheel and eyes on the road, as some assume.

The combustion process after auto-ignition is investigated. Depending on the non-uniformity of the end gas, auto-ignition could initiate a flame, produce pressure waves that excite the engine structure (acoustic knock), or result in detonation (normal or developing). For the “acoustic knock” mode, a knock intensity (KI) is defined as the pressure oscillation amplitude. The KI values over different cycles under a fixed operating condition are observed to have a log-normal distribution. When the operating condition is changed (over different values of λ, EGR, and spark timing), the mean (μ) of log (KI/GIMEP) decreases linearly with the correlation-based ignition delay calculated using the knock-point end gas condition of the mean cycle. The standard deviation σ of log(KI/GIMEP) is approximately a constant, at 0.63. The values of μ and σ thus allow a statistical description of knock from the deterministic calculation of the ignition delay using the mean cycle properties

Meeting radiation protection requirements during EVA is predominantly an operational issue with some potential considerations for temporary shelter. The issue of spacesuit shielding is mainly guided by the potential of accidental exposure when operational and temporary shelter considerations fail to maintain exposures within operational limits. In this case, very high exposure levels are possible which could result in observable health effects and even be life threatening. Under these assumptions, potential spacesuit radiation exposures have been studied using known historical solar particle events to gain insight on the usefulness of modification of spacesuit design in which the control of skin exposure is a critical design issue and reduction of blood forming organ exposure is desirable.

An ADvanced Automotive Manikin (ADAM) developed at the National Renewable Energy Laboratory (NREL) is used to evaluate NASA’s liquid cooling garments (LCGs) used in advanced spacesuits. The manikin has 120 separate heated/sweating zones and is controlled by a finite-element physiological model of the human thermo-regulatory system. Previous testing showed the thermal sensation and comfort followed expected trends as the LCG inlet fluid temperature was changed. The Phase II test data demonstrates the repeatability of ADAM by retesting the baseline LCG. Skin and core temperature predictions using ADAM in an LCG/arctic suit combination are compared to NASA physiological data to validate the manikin/model. An additional Orlan LCG configuration is assessed using the manikin and compared to the baseline LCG.

One of the risks associated with long-term space flights is cancer incidence resulting from chronic exposure to space radiation. Assessment of incurred risk from radiation exposure requires quantifying the dose throughout the body. The space radiation exposure received by Space Shuttle astronauts is measured by thermoluminescent dosimeters (TLDs) worn during every mission. These dosimeters measure the absorbed dose to the skin, but the dose to internal organs is required for estimating the cancer risk induced by space radiation. A method to extrapolate these skin dose measurements to realistic organ specific dose estimates, using the Computerized Anatomical Man (CAM) and Computerized Anatomical Female (CAF) models, is discussed in detail. A transport code, which propagates high energy nucleon and charged particles, is combined with the CAM/CAF-generated shielding areal distributions to evaluate the absorbed dose at selected organ sites.

In this paper we investigate the optimal forming of conical cups of AL 2008-T4 through the use of real-time process control. We consider a flat, frictional binder the force of which can be determined precisely through closed-loop control. Initially the force is held constant throughout the forming of the cup, and various levels of force are tested experimentally and with numerical simulation. Excellent agreement between experiment and simulation is observed. The effects of binder force on cup shape, thickness distribution, failure mode and cup failure height are investigated, and an “optimal” constant binder force is determined. For this optimal case, the corresponding punch force is recorded as a function of punch displacement and is used in subsequent closed-loop control experiments. In addition to the constant force test, a trial variable binder force test was performed to extend the failure height beyond that obtained using the “optimal” constant force level.

Vibrational disturbance magnitude and frequency on space-flight missions is often a critical factor regarding mission success. Both materials processing experiments and astronomical investigations have specific microgravity environmental requirements. Recent efforts have been made to quantify the microgravity environment on the Space Shuttle Columbia by measuring gravity levels produced by specific mission events such as Orbiter engine burns, treadmill and ergometer activities, crew sleep periods, rotating chair operations, and body mass measurement operations. However, no measurements have been made of specific, nominal crewmember activities such as translating about the middeck, flight-deck, or in the Spacelab. This report presents pilot-study data of test subject forces induced by intravehicular activities such as push-offs and landings with both hands and feet. Five subjects participated in this investigation.

The incidence of DCS in null gravity appears to be considerably less than predicted by 1-g experiments. In NASA studies in 1-g, 83% of the incidents of DCS occur in the legs. We report first on a study with a crossover design that indicated a considerable reduction in the decompression Doppler bubble grade in the lower extremities in subjects in simulated microgravity (bed rest) as compared to themselves when ambulatory in unit gravity. Second we describe the results of a cardiovascular deconditioning study using a tail-suspended rat model. Since there may be a reduction in bubble production in 0-g, this would reduce the possibility of acquiring neurological DCS, especially by arterial gas embolism. Further, cardiovascular deconditioning appears to reduce the pulmonary artery hypertension (secondary to gas embolization) necessary to effect arterialization of bubbles.

The Self Contained Atmospheric Protective Ensemble (SCAPE) suits, worn at the Kennedy Space Center (KSC) have been updated from the original 1970's design. The suits were renamed Propellant Handlers Ensemble (PHE) but are still commonly referred to as SCAPE. Several modifications to the suit were done over the last 20 years to improve the design for operational use. However, anthropometric changes in the user population over time have not been addressed. The following study addressed anthropometric concerns in the current SCAPE population. It was found that all suits had at least one area in which the recommended upper limit was exceeded by technicians. The most common areas to exceed the upper limit were: waist circumference, chest circumference and upper thigh circumference. Forearm circumference posed the least concern unless using long gauntlet glove which cause the twist lock ring to be located at the forearm rather than the wrist.

Human explorers of planetary surfaces would benefit greatly from a spacesuit design that facilitates locomotion. To aid in the development of such an extravehicular activity suit, a design effort incorporating the concept of mechanical counter pressure (MCP) was undertaken. Three-dimensional laser scanning of the human body was used to identify the main effects of knee flexion angle on the size and shape of the leg. This laser scanning quantified the changes in shape that must be supported by an MCP garment and the tension that must be developed to produce even MCP. Evaluation of a hybrid-MCP concept using inextensible materials demonstrated strong agreement between experimental data and a mathematical model with rigid cylinder geometry. Testing of a form-fitting garment on the right lower leg of a subject demonstrated successful pressure production. Further research is required to evaluate how evenly pressure can be distributed using the hybrid-MCP concept.

The Urban Vehicle Design Competition was inspired by the success of the Clean Air Car Race and the Great Electric Car Race. The academic community recognized the tremendous educational value of these events, and encouraged development of UVDC from its inception. The project was designed by engineering students to benefit students throughout North America. The rules of the competition include technical paper requirements that make the competition extremely attractive to professors who wish to build a course around this theme. The response of more than 2000 engineering students at 80 universities throughout the United States and Canada has indicated the success of the structure of the competition. The first major objective of the UVDC project has been met. Ninety-three teams throughout the country entered the UVDC design portion of the contest. The second portion of the project is the prototype contest of August 1972.

Measurements were made of exhaust histories of the following species: unburned hydrocarbons (HC), carbon monoxide, carbon dioxide, oxygen, and nitric oxide (NO). The measurements show that the exhaust flow can be divided into two distinct phases: a leading gas low in HC and high in NO followed by a trailing gas high in HC and low in NO. Calculations of time resolved equivalence ratio throughout the exhaust process show no evidence of a stratified combustion. The exhaust mass flow rate is time resolved by forcing the flow to be locally quasi-steady at an orifice placed in the exhaust pipe. The results with the quasi-steady assumption are shown to be consistent with the measurements. Predictions are made of time resolved mass flow rate which compare favorably to the experimental data base. The composition and flow histories provide sufficient information to calculate the time resolved flow rates of the individual species measured.