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After several decades of human spaceflight, the community of space-faring nations has accumulated a diverse and sometimes harrowing history of toxicological events that have plagued human space endeavors almost from the very beginning. Some lessons have been learned in ground-based test beds and others were discovered the hard way - when human lives were at stake in space. From such lessons one can build a risk-management framework for toxicological events to minimize the probability of a harmful exposure, while recognizing that we cannot predict all possible events. Space toxicologists have learned that relatively harmless compounds can be converted by air revitalization systems into compounds that cause serious harm to the crew.

The NASA-wide CEV Smart Buyer Team (SBT) was assembled in January 2006 and was tasked with the development of a NASA in-house design for the CEV Crew Module (CM), Service Module (SM), and Launch Abort System (LAS). This effort drew upon over 250 engineers from all of the 10 NASA Centers. In 6 weeks, this in-house design was developed. The Thermal Systems Team was responsible for the definition of the active and passive design architecture. The SBT effort for Thermal Systems can be best characterized as a design architecting activity. Proof-of-concepts were assessed through system-level trade studies and analyses using simplified modeling. This nimble design approach permitted definition of a point design and assessing its design robustness in a timely fashion. This paper will describe the architecting process and present trade studies and proposed thermal designs

In preparation for the contract award of the Crew Exploration Vehicle (CEV), the National Aeronautics and Space Administration (NASA) produced two design reference missions for the vehicle. The design references used teams of engineers across the agency to come up with two configurations. This process helped NASA understand the conflicts and limitations in the CEV design, and investigate options to solve them.

An EVA simulation with a medical contingency scenario was conducted in 2006 with the NASA Haughton-Mars and EVA Physiology System and Performance Projects, to develop medical contingency management and evacuation techniques for planetary surface exploration. A rescue/evacuation system to allow two rescuer astronauts to evacuate one incapacitated astronaut was evaluated. The rescue system was utilized effectively to extract an injured astronaut up a slope of15-25° and into a surface mobility rover for transport to a simulated habitat for advanced medical care. Further research is recommended to evaluate the effects of reduced gravity and to develop synergies with other surface systems for carrying out the contingency procedures.

Providing water necessary to maintain life support has been accomplished in spacecraft vehicles for over forty years. This paper will investigate how previous U.S. space vehicles provided potable water. The water source for the spacecraft, biocide used to preserve the water on-orbit, water stowage methodology, materials, pumping mechanisms, on-orbit water requirements, and water temperature requirements will be discussed. Where available, the hardware used to provide the water and the general function of that hardware will also be detailed. The Crew Exploration Vehicle (CEV or Orion) water systems will be generically discussed to provide a glimpse of how similar they are to water systems in previous vehicles. Conclusions, questions, and recommendations on strategies that could be applied to CEV based on previous spacecraft water system lessons learned will be made.

This project investigates methods to capture an astronaut's exhaled carbon dioxide (CO2) before it becomes diluted with the high volumetric oxygen flow present within a space suit. Typical expired breath contains CO2 partial pressures (pCO2) in the range of 20-35 mm Hg (.0226-.046 atm). This research investigates methods to capture the concentrated CO2 gas stream prior to its dilution with the low pCO2 ventilation flow. Specifically this research is looking at potential designs for a collection cup for use inside the space suit helmet. The collection cup concept is not the same as a breathing mask typical of that worn by firefighters and pilots. It is well known that most members of the astronaut corps view a mask as a serious deficiency in any space suit helmet design. Instead, the collection cup is a non-contact device that will be designed using a detailed Computational Fluid Dynamic (CFD) analysis of the ventilation flow environment within the helmet.

An energy balance was performed on the life support equipment used during the Phase III, 90-day, human Lunar-Mars Life Support Test Project at the Johnson Space Center. The purpose of the analysis was to account for all the energy sources, uses, and losses in the test-bed. Knowledge from this task may allow more energy efficient designs to be developed. Control volumes were defined and energy balance equations were generated for major systems. The analyses succeeded in balancing the energy fairly well for several systems. Further, the data showed that inefficiencies existed, and means of design optimization were subsequently suggested.

A phase change material (PCM) heat sink using super cooled ice as a non-toxic, non-flammable PCM is being developed for use in a portable life support system (PLSS). The latent heat of fusion for water is approximately 70% larger than most paraffin waxes, which can provide significant mass savings. Further mass reduction is accomplished by super cooling the ice significantly below its freezing temperature for additional sensible heat storage. Expansion and contraction of the water as it freezes and melts is accommodated with the use of flexible bag and foam materials. A demonstrator unit has been designed, built, and tested to demonstrate proof of concept. Both testing and modeling results are presented.

Absorption cooling using a lithium chloride/water heat pump can enable lightweight and effective thermal control for Extravehicular Activity (EVA) suits without venting water to the environment. The key components in the system are an absorber/radiator that rejects heat to space and a flexible evaporation cooling garment that absorbs heat from the crew member, This paper describes progress in the design, development, and testing of the absorber/radiator and evaporation cooling garment. New design concepts and fabrication approaches will significantly reduce the mass of the absorber/radiator. We have also identified materials and demonstrated fabrication approaches for production of a flexible evaporation cooling garment, Data from tests of the system's modular components have validated the design models and allowed predictions of the size and weight of a complete system.

Lunar dust exposures occurred during the Apollo missions while the crew was in the lunar module on the moon's surface and especially when micro-gravity conditions were attained during rendezvous in lunar orbit. Crews reported that the dust was irritating to the eyes, and in some cases, respiratory symptoms were elicited. NASA's current vision for lunar exploration includes stays of 6 months on the lunar surface hence the health effects of periodic exposure to lunar dust in the habitat need to be assessed. NASA is performing this assessment with a series of in vitro and in vivo tests with authentic lunar dust. Our approach is to “calibrate” the intrinsic toxicity of lunar dust by comparison to a relatively low toxicity dust (TiO2) and a highly toxic dust (quartz) using intrapharyngeal instillation of the dusts to mice. A battery of indices of toxicity is assessed at various time points after the instillations.

Thermal control systems for space application plant growth chambers offer unique challenges. The ability to control temperature and humidity independently gives greater flexibility for optimizing plant growth. Desired temperature and relative humidity range vary widely from 15°C to 35°C and 65% to 85% respectively. On top of all of these variables, the thermal control system must also be conservative in power and mass. These requirements to develop and test a robust thermal control system for space applications led to the design and development of the Environmental System Test Stand (ESTS) at NASA Johnson Space Center (JSC). The ESTS was designed to be a size constrained, environmental control system test stand with the flexibility to allow for a variety of thermal and lighting technologies. To give greater understanding to the environmental control system, the development of the ESTS included both mathematical models and the physical test stand.

The International Space Station (ISS) Active Thermal Control System (ATCS) (Ref. 1,2) has changed over the past several years to address problems and to improve its assembly and operation on-orbit. This paper captures the ways in which the Internal (I) ATCS and External (E) ATCS have changed design characteristics and operations both for the system currently operating on-orbit and the new elements of the system that are about to be added and/or activated. The rationale for changes in ATCS design, assembly and operation will provide insights into the lessons learned during ATCS development. The state of the assembly of the integrated ATCS will be presented to provide a status of the build-up of the system. The capabilities of the on-orbit system will be presented with a summary of the elements of the ISS ATCS that are functional on-orbit plus the plans for launch of remaining parts of the integrated ISS ATCS.

Biological water processors are currently being developed for application in microgravity environments. Work has been performed to develop a single-phase, gravity independent anoxic denitrification reactor for organic carbon removal [1]. As a follow on to this work it was necessary to develop a gravity independent nitrification reactor in order to provide sufficient nitrite and nitrate to the organic carbon oxidation reactor for the complete removal of organic carbon. One approach for providing the significant amounts of dissolved oxygen required for nitrification is to require the biological reactor design to process two-phase gas and liquid in micro-gravity. This paper addresses the design and test results overview for development of a tubular, two-phase, gravity independent nitrification biological water processor.

The INTEGRITY Program will design and operate a test bed facility to help prepare for future beyond-LEO missions. The purpose of INTEGRITY is to enable future missions by developing, testing, and demonstrating advanced human space systems. INTEGRITY will also implement and validate advanced management techniques including risk analysis and mitigation. One important way INTEGRITY will help enable future missions is by reducing their risk. A risk analysis of human space missions is important in defining the steps that INTEGRITY should take to mitigate risk. This paper describes how a Probabilistic Risk Assessment (PRA) of human space missions will help support the planning and development of INTEGRITY to maximize its benefits to future missions. PRA is a systematic methodology to decompose the system into subsystems and components, to quantify the failure risk as a function of the design elements and their corresponding probability of failure.

The purification of waste water is a critical element of any long-duration space mission. The Vapor Phase Catalytic Ammonia Removal (VPCAR) system offers the promise of a technology requiring low quantities of expendable material that is suitable for exploration missions. NASA has funded an effort to produce an engineering development unit specifically targeted for integration into the NASA Johnson Space Center's Integrated Human Exploration Mission Simulation Facility (INTEGRITY) formally known in part as the Bioregenerative Planetary Life Support Test Complex (Bio-Plex) and the Advanced Water Recovery System Development Facility. The system includes a Wiped-Film Rotating-Disk (WFRD) evaporator redesigned with micro-gravity operation enhancements, which evaporates wastewater and produces water vapor with only volatile components as contaminants. Volatile contaminants, including organics and ammonia, are oxidized in a catalytic reactor while they are in the vapor phase.

Since the early 1980’s, the Shuttle Extra Vehicular Activity (EVA) glove design has evolved to meet the challenge of space based tasks. These tasks have typically been satellite retrieval and repair or EVA based flight experiments. With the start of the International Space Station (ISS) assembly, the number of EVA based missions is increasing far beyond what has been required in the past; this has commonly been referred to as the “Wall of EVA’s”. To meet this challenge, it was determined that the evolution of the current glove design would not meet future mission objectives. Instead, a revolution in glove design was needed to create a high performance tool that would effectively increase crewmember mission efficiency. The results of this effort have led to the design, certification and implementation of the Phase VI EVA glove into the Shuttle flight program.

This paper provides an overview of the IMMWPS Integrated Ground Test Program, completed at the NASA Johnson Space Center (JSC) during October and November 2001. The JSC Crew and Thermal Systems Division (CTSD) has developed the IMMWPS orbital flight experiment to test the feasibility of a microbe-based water purifier for use in zero-gravity conditions. The IMMWPS design utilizes a Microbial Processor Assembly (MPA) inoculated with facultative anaerobes to convert organic contaminants in wastewater to carbon dioxide and biomass. The primary purpose of the ground test program was to verify functional operations and procedures. A secondary objective was to provide initial ground data for later comparison to on-orbit performance. This paper provides a description of the overall test program, including the test article hardware and the test sequence performed to simulate the anticipated space flight test program. In addition, a summary of significant results from the testing is provided.

A thermal analysis of the compressible carbon dioxide (CO2) flow for the Portable Fire Extinguisher (PFE) system has been performed. A SINDA/FLUINT model has been developed for this analysis. The model includes the PFE tank and the Temporary Sleep Station (TeSS) nozzle, and both have an initial temperature of 72 °F. In order to investigate the thermal effect on the nozzle due to discharging CO2, the PFE TeSS nozzle pipe has been divided into three segments. This model also includes heat transfer predictions for PFE tank inner and outer wall surfaces. The simulation results show that the CO2 discharge rates and component wall temperatures fall within the requirements for the PFE system. The simulation results also indicate that after 50 seconds, the remaining CO2 in the tank may be near the triple point (gas, liquid and solid) state and, therefore, restricts the flow.

The Major Constituent Analyzer (MCA) was activated on-orbit on 2/13/01 and provided essentially continuous readings of partial pressures for oxygen, nitrogen, carbon dioxide, methane, hydrogen and water in the ISS atmosphere. The MCA plays a crucial role in the operation of the Laboratory ECLSS and EVA operations from the airlock. This paper discusses the performance of the MCA as compared to specified accuracy requirements. The MCA has an on-board self-calibration capability and the frequency of this calibration could be relaxed with the level of instrument stability observed on-orbit. This paper also discusses anomalies the MCA experienced during the first year of on-orbit operation. Extensive Built In Test (BIT) and fault isolation capabilities proved to be invaluable in isolating the causes of anomalies. The process of fault isolation is discussed along with development of workaround solutions and implementation of permanent on-orbit corrections.

The quantitative analysis of the food system for long-term space missions is a crucial factor for the comparison of different food plans and for the evaluation of the food system as part of the overall mission. Such analysis should include important factors such as nutrition, palatability, diet cycle length, and psychological issues related to food. This paper will give the details of a mathematical model that was developed during the first author's participation as a Summer Faculty Fellow at Johnson Space Center. The model includes nutrition, palatability, diet cycle length, and psychological issues as important components. The model is compatible with the Equivalent System Mass (ESM) metric previously developed as the Advance Life Support (ALS) Research and Technology Metric.