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The Centrifuge Accommodation Module (CAM) is designed to be one of the modules of the International Space Station (ISS) for performing on-orbit science experiments over an extended period of time. The common cabin air assembly (CCAA) is utilized as the hardware for air temperature and humidity control (THC) for the CAM module cabin. The CCAA unit contains a variable speed fan, heat exchanger, temperature control valve, water separator, temperature sensor, and electrical interface box. A temperature and humidity simulation model was developed to perform the THC analysis for the CCAA unit inside the CAM. This model applies both fixed control volume and a quasi-steady-state approach for computing critical information for evaluating/assessing CCAA system performance and capabilities.