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This paper proposes the concept of Generalized Diagnostic Component (GDC) and presents a modular fault diagnostic strategy for safety critical automotive systems. The diagnostic strategy makes full use of hierarchical techniques, integrates the generalized diagnostic design into all-purpose vehicle diagnoses based on reconfiguration of the GDCs, and inherits the model-based diagnostic algorithms developed for Steering/Braking-By-Wire systems. The GDC-based approach simplifies the design and integration of diagnostics in complex dynamical control systems, and has been successfully implemented in an eight degrees of freedom NAVDyn (Non-Linear Analysis of Vehicle Dynamics) simulation model using Matlab Simulink. The simulation results are provided in this paper to testify that the diagnostic strategy and implementation are feasible, efficient and dependable.