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The GMR Driving Simulator was used to study the performance of four teen-aged, novice drivers, two of whom had cerebral palsy. The purpose of this pilot study was to determine the potential of the simulator to discriminate between the driving abilities of medically handicapped and non-handicapped individuals. The study concentrated on the psychomotor aspects of lane-keeping performance in the presence of road curvature and environmental disturbances. The study indicates that a dynamically realistic driving simulator could be a valuable screening device for identifying potential performance difficulties in handicapped individuals prior to behind-the-wheel instruction.