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New seal cross-section development is a very tedious and time consuming process if conventional analysis methods are used, as it is very difficult to predict the dimensions of the seal that will satisfy the sealing performance targets. In this study, a generic cross-section is defined and the design constraints are specified. Isight then runs the FEA model, utilizing a custom python script for post-processing. Isight then updates the dimensions of the seal and continues running analyses. Isight was run using two different design exploration techniques. The first was a design of experiments (DOE) to discover how the seal’s response varies with its dimensions. Then, after the analyst examined the results, Isight was run in optimization mode focusing on feasible design areas as determined from the DOE. Thus, after the initial model setup, the user can run the analyses in the background and only needs to interact with the program after Isight has determined a list of feasible designs.