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This study focuses on the development of an autoignition model for diesel sprays that is applicable to phenomenological multi-zone combustion models. These models typically use a single-step Arrhenius expression to represent the low-temperature chemistry leading up to autoignition. There has been a substantial amount of work done in the area of n-heptane autoignition in homogeneous mixtures. Reduced kinetic mechanisms with ten reactions or less have been proposed in the literature to represent the complex low-temperature oxidation of n-heptane. These kinetic models are attractive for multi-zone simulations because of the low number of reactions involved. However, these kinetic mechanisms and the multi-zone treatment of the fuel spray do not account for the effect of turbulence/chemistry interactions on the chemical reaction rate.