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The technical feasibility of applying anaerobic digestion for reduction and stabilization of the organic fraction of solid wastes generated during space missions was investigated. This process has the advantages of not requiring oxygen or high temperature and pressure while producing methane, carbon dioxide, nutrients, and compost as valuable products. High-solids leachbed anaerobic digestion employed here involves a solid-phase fermentation with leachate recycle between new and old reactors for inoculation, wetting, and removal of volatile organic acids during startup. After anaerobic conversion is complete, the compost bed may be used for biofiltration and plant growth medium. The nutrient-rich leachate may also be used as a vehicle for nutrient recycle. Physical properties of representative waste feedstocks were determined to evaluate their space requirements and hydraulic leachability in the selected digester design.