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This paper reports results of Computational Fluid Dynamics (CFD) analysis of carbon dioxide (CO2) gradient variations in twelve ISS modules. Computations were performed using two 3D integrated models: one from the U.S. Laboratory to the forward end, and the other from the U.S. Laboratory to the aft end of the ISS. Operation of the CO2 removal systems and CO2 generation among six International Space Station (ISS) crewmembers' metabolic processes were included in the model. For several crew location scenarios, a detailed analysis of the CO2 gradients and time evolution in zones potentially occupied by astronauts is presented. In general, the paper gives an extended example of the application of CFD analysis to complex problems related to the quality of the cabin air.

Crew health is dependent on the concentration of carbon dioxide in the atmosphere breathed. Often, models used for concentration have used the assumption that each module of the space station is well mixed, i.e. that the CO2 concentration is constant throughout the module. In this paper, Computational Fluid Dynamics (CFD) modeling is used to assess and validate the accuracy of that assumption. The concentration of carbon dioxide as calculated by CFD was compared to the concentration as calculated by a lumped parameter model. The assumption that the module is well mixed allows the use of relatively simple models, which can be developed and run quickly in order to support decisions for on-orbit analysis. CFD models generate more detailed information, such as CO2 gradients within the modules and airflow and mixing characteristics. However, CFD models, particularly transient models, take longer to develop and use.